抗磷脂抗体的共辅因子βGPI的研究进展

被引:9
作者
邓宇斌
机构
[1] 上海第二医科大学附属仁济医院上海市免疫学研究所
关键词
GPI; 辅因子; 血浆; 抗磷脂抗体; 抗原;
D O I
暂无
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
抗磷脂抗体的共辅因子β2GPI是一分子量为50kD的糖蛋白,由326个氨基酸组成,可分为5个功能区,期磷脂结合部位于第五功能区.众多事实表明自身免疫性疾病中的抗磷脂抗体作用的抗原是磷脂与β2GPI结合形成的复合抗原.β2GPI的抗原表位及与磷脂的关系研究,对于提示抗磷脂抗体的产生,抗磷脂抗体综合征的血栓发生病理制的研究具有重要意义.
引用
收藏
页码:61 / 62+36 +36
页数:3
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