神经保护药物治疗缺血性脑卒中的最新进展

被引:8
作者
徐恩
缪学琼
李雯
机构
[1] 广州医学院第二附属医院神经内科
关键词
神经保护药物; 缺血性脑卒中;
D O I
暂无
中图分类号
R743.3 [急性脑血管疾病(中风)];
学科分类号
摘要
神经保护药物主要作用于脑缺血引发的细胞毒性机制,在脑缺血瀑布启动前使用此类药物能更好地减轻缺血性脑损伤。本文对谷氨酸受体拮抗剂、自由基清除剂、γ-氨基丁酸(GABA)激动剂、胞二磷胆碱、炎症反应抑制剂、雌激素、促红细胞生成素等作了简要介绍。
引用
收藏
页码:38 / 41
页数:4
相关论文
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[1]   Functional and histological evidence for the protective effect of NXY-059 in a primate model of stroke when given 4 hours after occlusion [J].
Marshall, JWB ;
Cummings, RM ;
Bowes, LJ ;
Ridley, RM ;
Green, AR .
STROKE, 2003, 34 (09) :2228-2233
[2]  
Oral Citicoline in Acute Ischemic Stroke: An Individual Patient Data Pooling Analysis of Clinical Trials[J] . Antoni Dávalos,José Castillo,José álvarez-Sabín,Julio J. Secades,Joan Mercadal,Sonia López,Erik Cobo,Steven Warach,David Sherman,Wayne M. Clark,Rafael Lozano.Stroke: Journal of the American Heart Association . 2002 (12)
[3]  
Neuroprotective Effects of a Novel Non–Receptor-Binding Estrogen Analogue: In Vitro and In Vivo Analysis[J] . Ran Liu,Shao-Hua Yang,Evelyn Perez,Kun Don Yi,Samuel S. Wu,Kathleen Eberst,Laszlo Prokai,Katalin Prokai-Tatrai,Zu Yun Cai,Douglas F. Covey,Arthur L. Day,James W. Simpkins.Stroke: Journal of the American Heart Association . 2002 (10)
[4]  
Clomethiazole Acute Stroke Study in Ischemic Stroke (CLASS-I): Final Results[J] . P. Lyden,A. Shuaib,K. Ng,K. Levin,R. P. Atkinson,A. Rajput,L. Wechsler,T. Ashwood,L. Claesson,T. Odergren,E. Salazar-Grueso.Stroke: Journal of the American Heart Association . 2002 (1)
[5]  
Examination of Several Potential Mechanisms for the Negative Outcome in a Clinical Stroke Trial of Enlimomab, a Murine Anti-Human Intercellular Adhesion Molecule-1 Antibody: A Bedside-to-Bench Study[J] . Kazuhide Furuya,Hidetaka Takeda,Salman Azhar,Richard M. McCarron,Yong Chen,Christl A. Ruetzler,Karen M. Wolcott,Thomas J. DeGraba,Robert Rothlein,Tony E. Hugli,Gregory J. del Zoppo,John M. Hallenbeck.Stroke: Journal of the American Heart Association . 2001 (11)
[6]  
Very Early Nimodipine Use in Stroke (VENUS): A Randomized, Double-Blind, Placebo-Controlled Trial[J] . J. Horn,R.J. de Haan,M. Vermeulen,M. Limburg.Stroke: Journal of the American Heart Association . 2001 (2)
[7]  
Selfotel in Acute Ischemic Stroke: Possible Neurotoxic Effects of an NMDA Antagonist[J] . Stephen M. Davis,Kennedy R. Lees,Gregory W. Albers,Hans Christoph Diener,Sabri Markabi,Goeril Karlsson,John Norris.Stroke: Journal of the American Heart Association . 2000 (2)