帕金森病发病机制研究进展:α-synuclein与氧化应激

被引:6
作者
戚辰
刘振国
机构
[1] 上海第二医科大学附属瑞金医院神经内科帕金森病诊疗与研究中心,上海第二医科大学附属瑞金医院神经内科帕金森病诊疗与研究中心上海,上海
关键词
帕金森病; 发病机制; α-synuclein; 氧化应激;
D O I
暂无
中图分类号
R742.5 [震颤麻痹综合征];
学科分类号
1002 ;
摘要
帕金森病 (PD)是一种常见的老年神经变性疾病 ,它的发病机制与遗传因素和环境因素共同作用有关 ,但其内在的联系尚不十分清楚。α synuclein可能起到联系基因和环境因素在PD中的发病机制的作用 ,而多巴胺导致的氧化应激则可能是神经变性的共同途径。本文就α synuclein和氧化应激在PD发病机制中作用等方面的研究作一综述
引用
收藏
页码:327 / 331
页数:5
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