静脉注射免疫球蛋白免疫调节机制的研究进展

被引:12
作者
曹志然
陈淑兰
机构
[1] 河北大学医学部
关键词
静脉注射免疫球蛋白; 免疫调节机制; 免疫细胞;
D O I
暂无
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
静脉注射免疫球蛋白(intravenous immunoglobulin,IVIg)可调节机体的免疫功能,其调节机制主要通过:①抑制免疫细胞的增殖与活化。②调节免疫细胞的凋亡。③抑制免疫细胞的黏附与吞噬。④调节细胞因子的合成与分泌。⑤抑制补体系统的活性。⑥中和超抗原对免疫细胞的激活作用。高剂量静脉注射免疫球蛋白(high dose IVIg,hd IVIg)作为免疫调节剂越来越多的被用于免疫功能紊乱患者。本文综述了hdIVIg在免疫调节作用机制方面的最新发现和进展。
引用
收藏
页码:1026 / 1028
页数:3
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