肿瘤坏死因子α与血管内皮生长因子在烟雾暴露大鼠肺气肿模型中的动态变化

Pulmonary hypertension in TNFalpha-overexpressing mice is associated with decreased VEGF gene expression. Fujita M,Mason RJ,Cool C,et al. Journal of Applied Physiology . 2002

Downregulation of vascular endothelial growth factor receptors by tumor necrosis factoralpha in cultured human vascular endothelial cells. Patterson C,Perrella MA,Endege WO,et al. The Journal of Clinical Investigation . 1996

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. Kasahara Y,Tuder RM,Taraseviciene-Stewart L,et al. The Journal of Clinical Investigation . 2000

Overexpression of tumor necrosis factor-alpha produces an increase in lung volumes and pulmonary hypertension. Fujita M,Shannon JM,Irvin CG,et al. American Journal of Physiology Lung Cellular and Molecular Physiology . 2001

Pulmonary hypertension in TNFalpha-overexpressing mice is associated with decreased VEGF gene expression. Fujita M,Mason RJ,Cool C,et al. Journal of Applied Physiology . 2002

Downregulation of vascular endothelial growth factor receptors by tumor necrosis factoralpha in cultured human vascular endothelial cells. Patterson C,Perrella MA,Endege WO,et al. The Journal of Clinical Investigation . 1996

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. Kasahara Y,Tuder RM,Taraseviciene-Stewart L,et al. The Journal of Clinical Investigation . 2000

Overexpression of tumor necrosis factor-alpha produces an increase in lung volumes and pulmonary hypertension. Fujita M,Shannon JM,Irvin CG,et al. American Journal of Physiology Lung Cellular and Molecular Physiology . 2001