共 5 条
多囊卵巢综合征患者血清瘦素水平与性激素间的相关性研究
被引:14
作者:

岳峰
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机构: 泰安市中心医院内分泌一科

张铁
论文数: 0 引用数: 0
h-index: 0
机构: 泰安市中心医院内分泌一科

李秀莲
论文数: 0 引用数: 0
h-index: 0
机构: 泰安市中心医院内分泌一科
机构:
[1] 泰安市中心医院内分泌一科
关键词:
多囊卵巢综合征;
瘦素;
D O I:
暂无
中图分类号:
R711.75 [卵巢疾病];
学科分类号:
100211 [妇产科学];
摘要:
目的探讨多囊卵巢综合征(PCOS)患者血清瘦素(leptin)水平与性激素的相关性。方法选择初诊的PCOS患者34例作为研究对象,选择年龄及体重指数(BMI)相匹配的健康女性作为对照组进行血清瘦素、空腹血糖(FBG)、空腹胰岛素(FIn)、尿促卵泡素(FSH)、黄体生成素(LH)、孕激素(P)/雌激素(E)及睾酮(T)测定,并对它们间的相关性进行分析。结果 PCOS患者血清瘦素、LH、LH/FSH、T、BMI、FBG、胰岛素抵抗指数(HOMA-IR)水平均显著高于对照组,而FSH水平显著降低。血清瘦素水平与BMI、FBG、FIn及HOMA-IR存在相关性,进一步多元回归分析提示,血清瘦素与BMI独立相关。结论 PCOS患者血清瘦素水平变化与肥胖、糖代谢紊乱及性激素代谢异常有一定关系。
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页码:590 / 592
页数:3
相关论文
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