银屑病的免疫学机制与治疗靶点

被引：66

作者：

吴玥

王宏林

机构：

[1] 上海交通大学医学院上海市免疫学研究所

来源：

中国免疫学杂志 | 2019年 / 35卷 / 11期

基金：

国家杰出青年科学基金;

关键词：

银屑病; 角质形成细胞; T淋巴细胞; 白细胞介素-17;

D O I：

暂无

中图分类号：

R758.63 [牛皮癣（银屑病）];

学科分类号：

100227 [皮肤病学];

摘要：

银屑病是一种主要危害人体皮肤健康的慢性炎症性疾病,与遗传、感染与免疫等因素密切相关。除皮肤中主要的角质形成细胞与成纤维细胞外,来源自免疫系统的其他细胞与分子在银屑病的发病机制中也扮演了重要的角色,靶向免疫系统的疗法经过数十年的发展呈现良好的安全性和有效性。本文就银屑病中关键的免疫细胞、分子机制及治疗靶点作一综述。

引用

页码：1281 / 1288

页数：8

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