Toll样受体的内源性激活在糖尿病及糖尿病肾病中的作用——TLRs表达、激活促进DM和DN的发生、发展

被引：9

作者：

袁婷

关晓菲

卢文冉

尹晓琳

魏琳

机构：

[1] 河北医科大学免疫实验室河北省重大疾病的免疫机制及干预重点实验室

来源：

中国免疫学杂志 | 2015年 / 31卷 / 08期

关键词：

D O I：

暂无

中图分类号：

R587.2 [糖尿病性昏迷及其他并发症];

学科分类号：

100201 [内科学];

摘要：

<正>近年来,随着人们生活水平的提高,饮食习惯的改变,平均寿命的延长,糖尿病(Diabetes mellitus,DM)的发病率明显增高。糖尿病肾病(Diabetic nephropathy,DN)是在糖尿病病程中出现的以蛋白尿、肾功能不全等肾脏病变为特征的疾病,是糖尿病常见的并发症之一。越来越多的人认识到糖尿病肾病是由新陈代谢紊乱、蛋白质过载和血流动力学异常激活了炎症因素而导致的。Toll样受体(Toll-like

引用

页码：1124 / 1128

页数：5

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