法尼醇X受体对代谢调控作用的研究进展

被引：14

作者：

颜勇 ^{[1
]}

李旭忠 ^{[2
]}

周舟 ^{[3
]}

胡承 ^{[3
]}

张学利 ^{[1
]}

机构：

[1] 上海, 南方医科大学附属奉贤区中心医院普外科

[2] 苏州大学临床医学院

[3] 上海交通大学附属第六人民医院内分泌代谢科上海市糖尿病研究所

来源：

中华糖尿病杂志 | 2016年 / 8卷 / 05期

关键词：

D O I：

暂无

中图分类号：

R58 [内分泌腺疾病及代谢病];

学科分类号：

100201 [内科学];

摘要：

<正>

引用

收藏

相关论文

共 29 条

[1]

Farnesoid X receptor–induced lysine‐specific histone demethylase reduces hepatic bile acid levels and protects the liver against bile acid toxicity.[J].Young‐Chae Kim;Sungsoon Fang;Sangwon Byun;Sunmi Seok;Byron Kemper;Jongsook Kim Kemper.Hepatology.2015, 1

[2]

Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial [J].

Neuschwander-Tetri, Brent A. ;

Loomba, Rohit ;

Sanyal, Arun J. ;

Lavine, Joel E. ;

Van Natta, Mark L. ;

Abdelmalek, Manal F. ;

Chalasani, Naga ;

Dasarathy, Srinivasan ;

Diehl, Anna Mae ;

Hameed, Bilal ;

Kowdley, Kris V. ;

McCullough, Arthur ;

Terrault, Norah ;

Clark, Jeanne M. ;

Tonascia, James ;

Brunt, Elizabeth M. ;

Kleiner, David E. ;

Doo, Edward .

LANCET, 2015, 385 (9972) :956-965

[3]

Recent advances in the development of farnesoid X receptor agonists [J].

Ali, Ahmad H. ;

Carey, Elizabeth J. ;

Lindor, Keith D. .

ANNALS OF TRANSLATIONAL MEDICINE, 2015, 3 (01)

[4]

Glucose Sensing O-GlcNAcylation Pathway Regulates the Nuclear Bile Acid Receptor Farnesoid X Receptor (FXR) [J].

Berrabah, Wahiba ;

Aumercier, Pierrette ;

Gheeraert, Celine ;

Dehondt, Helene ;

Bouchaert, Emmanuel ;

Alexandre, Jeremy ;

Ploton, Maheul ;

Mazuy, Claire ;

Caron, Sandrine ;

Tailleux, Anne ;

Eeckhoute, Jerome ;

Lefebvre, Tony ;

Staels, Bart ;

Lefebvre, Philippe .

HEPATOLOGY, 2014, 59 (05) :2022-2033

[5]

Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease [J].

Mudaliar, Sunder ;

Henry, Robert R. ;

Sanyal, Arun J. ;

Morrow, Linda ;

Marschall, Hanns-Ulrich ;

Kipnes, Mark ;

Adorini, Luciano ;

Sciacca, Cathi I. ;

Clopton, Paul ;

Castelloe, Erin ;

Dillon, Paul ;

Pruzanski, Mark ;

Shapiro, David .

GASTROENTEROLOGY, 2013, 145 (03) :574-+

[6]

Synthetic FXR Agonist GW4064 Prevents Diet-Induced Hepatic Steatosis and Insulin Resistance [J].

Ma, Yongjie ;

Huang, Yixian ;

Yan, Linna ;

Gao, Mingming ;

Liu, Dexi .

PHARMACEUTICAL RESEARCH, 2013, 30 (05) :1447-1457

[7]

Farnesoid X receptor targeting to treat nonalcoholic steatohepatitis.[J].Luciano Adorini;Mark Pruzanski;David Shapiro.Drug Discovery Today.2012, 17-1

[8]

Farnesoid X Receptor Induces Murine Scavenger Receptor Class B Type I via Intron Binding [J].

Li, Guodong ;

Thomas, Ann M. ;

Williams, Jessica A. ;

Kong, Bo ;

Liu, Jie ;

Inaba, Yuka ;

Xie, Wen ;

Guo, Grace L. .

PLOS ONE, 2012, 7 (04)

[9]

Selective Activation of Nuclear Bile Acid Receptor FXR in the Intestine Protects Mice Against Cholestasis [J].

Modica, Salvatore ;

Petruzzelli, Michele ;

Bellafante, Elena ;

Murzilli, Stefania ;

Salvatore, Lorena ;

Celli, Nicola ;

Di Tullio, Giuseppe ;

Palasciano, Giuseppe ;

Moustafa, Tarek ;

Halilbasic, Emina ;

Trauner, Michael ;

Moschetta, Antonio .

GASTROENTEROLOGY, 2012, 142 (02) :355-U269

[10]

糖尿病与非酒精性脂肪性肝病 [J].

范竹萍 ;

赵雄 .

中华糖尿病杂志, 2009, 1 (04)