表观遗传学在自身免疫性甲状腺疾病中的研究进展

被引：4

作者：

梁钟智

于红松

机构：

[1] 遵义医科大学免疫学教研室/贵州省基因检测与治疗特色重点实验室

来源：

遵义医学院学报 | 2019年 / 42卷 / 04期

关键词：

自身免疫性甲状腺疾病; 表观遗传学; DNA甲基化; 组蛋白修饰; 非编码RNA;

D O I：

10.14169/j.cnki.zunyixuebao.2019.0096

中图分类号：

R581 [甲状腺疾病];

学科分类号：

100201 [内科学];

摘要：

自身免疫性甲状腺疾病(Autoimmune thyroid diseases,AITD)是一组器官特异性自身免疫性疾病,其确切的发病机制尚未明确,现有研究表明AITD发生发展与遗传、环境及表观遗传学因素密切相关。本文主要综述DNA甲基化、组蛋白修饰、微小RNA和长链非编码RNA等表观遗传学因素在AITD中的最新研究进展。

引用

页码：475 / 480

页数：6

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