Exosome and epithelial-mesenchymal transition: A complex secret of cancer progression

被引：27

作者：

Dhar, Rajib ^{[1
]}

Devi, Arikketh ^{[1
]}

Gorai, Sukhamoy ^{[2
]}

Jha, Saurabh Kumar ^{[3
,4
,5
]}

Alexiou, Athanasios ^{[6
,7
]}

Papadakis, Marios ^{[8
,9
]}

机构：

[1] SRM Inst Sci & Technol, Dept Genet Engn, Canc & Stem Cell Biol Lab, Kattankulathur, India

[2] Rush Univ, Med Ctr, Chicago, IL USA

[3] Sharda Univ, Sch Engn & Technol SET, Dept Biotechnol, Greater Noida, India

[4] Chandigarh Univ, Dept Biotechnol Engn & Food Technol, Mohali, India

[5] Uttaranchal Univ, Sch Appl & Life Sci SALS, Dept Biotechnol, Dehra Dun, India

[6] Novel Global Community Educ Fdn, Dept Sci & Engn, Hebersham, NSW, Australia

[7] AFNP Med, Vienna, Austria

[8] Univ Hosp Witten Herdecke, Dept Surg 2, Witten, Germany

[9] Univ Witten Herdecke, Univ Hosp Witten Herdecke, Dept Surg 2, Heusner str 40, D-42283 Wuppertal, Germany

来源：

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE | 2023年 / 27卷 / 11期

关键词：

anti-metastasis therapeutic development; cancer; epithelial to mesenchymal transition; metastasis; organ-specific metastasis; TUMOR; CELLS;

D O I：

10.1111/jcmm.17755

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

This short communication will enlighten the readers about the exosome and the epithelial-mesenchymal transition (EMT) related to several complicated events. It also highlighted the therapeutic potential of exosomes against EMT. Exosome toxicology, exosome heterogeneity, and a single exosome profiling approach are also covered in this article. In the future, exosomes could help us get closer to cancer vaccine and precision oncology.

引用

页码：1603 / 1607

页数：5

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