Edoxaban versus Warfarin for Venous Thromboembolism Reply

被引:9
作者
Bueller, Harry R. [1 ]
机构
[1] Univ Amsterdam, Acad Med Ctr, NL-1105 AZ Amsterdam, Netherlands
关键词
D O I
10.1056/NEJMc1313883
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
To the Editor: In the study of edoxaban versus warfarin, the Hokusai-VTE Investigators (Oct. 10 issue)(1) found a significant decrease in the incidence of clinically relevant bleeding in the edoxaban group and a similar (though somewhat lower) incidence of major bleeding, as compared with that in the warfarin group. The definition of major bleeding a requirement for transfusion of 2 or more units of blood or a decrease in hemoglobin of 2 g per deciliter or more is similar to the definition used in most of the studies comparing the new anti-Xa or antithrombin agents with warfarin. The ...
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页码:80 / 81
页数:2
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