Clinical consequences of iron overload in hemochromatosis homozygotes

被引:47
作者
Ajioka, RS [1 ]
Kushner, JP [1 ]
机构
[1] Univ Utah, Sch Med, Dept Internal Med, Div Hematol, Salt Lake City, UT 84112 USA
关键词
D O I
10.1182/blood-2002-11-3453
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:3351 / 3354
页数:4
相关论文
共 32 条
[1]  
Allen KJ, 2002, LANCET, V360, P412, DOI 10.1016/S0140-6736(02)09583-1
[2]  
Åsberg A, 2001, SCAND J GASTROENTERO, V36, P1108
[3]   Association of mutations in the hemochromatosis gene with shorter life expectancy [J].
Bathum, L ;
Christiansen, L ;
Nybo, H ;
Ranberg, KA ;
Gaist, D ;
Jeune, B ;
Petersen, NE ;
Vaupel, J ;
Christensen, K .
ARCHIVES OF INTERNAL MEDICINE, 2001, 161 (20) :2441-2444
[4]   The HFE Cys282Tyr mutation as a necessary but not sufficient cause of clinical hereditary hemochromatosis [J].
Beutler, E .
BLOOD, 2003, 101 (09) :3347-3350
[5]   Penetrance of 845G→A (C282Y) HFE hereditary haemochromatosis mutation in the USA [J].
Beutler, E ;
Felitti, VJ ;
Koziol, JA ;
Ho, NJ ;
Gelbart, T .
LANCET, 2002, 359 (9302) :211-218
[6]   Hemochromatosis-associated morbidity in the United States: An analysis of the National Hospital Discharge Survey, 1979-1997 [J].
Brown, AS ;
Gwinn, M ;
Cogswell, ME ;
Khoury, MJ .
GENETICS IN MEDICINE, 2001, 3 (02) :109-111
[7]   Disease-related conditions in relatives of patients with hemochromatosis. [J].
Bulaj, ZJ ;
Ajioka, RS ;
Phillips, JD ;
LaSalle, BA ;
Jorde, LB ;
Griffen, LM ;
Edwards, CQ ;
Kushner, JP .
NEW ENGLAND JOURNAL OF MEDICINE, 2000, 343 (21) :1529-1535
[8]   Clinical and biochemical abnormalities in people heterozygous for hemochromatosis [J].
Bulaj, ZJ ;
Griffen, LM ;
Jorde, LB ;
Edwards, CQ ;
Kushner, JP .
NEW ENGLAND JOURNAL OF MEDICINE, 1996, 335 (24) :1799-1805
[9]  
Cox T, 2002, LANCET, V360, P412, DOI 10.1016/S0140-6736(02)09582-X
[10]   HEREDITARY HEMOCHROMATOSIS - ANALYSIS OF LABORATORY EXPRESSION OF THE DISEASE BY GENOTYPE IN 18 PEDIGREES [J].
DADONE, MM ;
KUSHNER, JP ;
EDWARDS, CQ ;
BISHOP, DT ;
SKOLNICK, MH .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 1982, 78 (02) :196-207