Welcome to the nucleus: CAN I take your coat?

被引:15
作者
Harel, A [1 ]
Forbes, DJ [1 ]
机构
[1] Univ Calif San Diego, Div Biol 0347, Sect Cell & Dev Biol, La Jolla, CA 92093 USA
关键词
D O I
10.1038/ncb1201-e267
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Individual viruses have evolved strategies for surmounting a formidable barrier in their path to replication in the nucleus - the nuclear envelope. A new study describing the nuclear entry of adenovirus 2 finds that this virus docks at the CAN/Nup214 protein of the nuclear pore, then hijacks histone HI and specific H1-import receptors to effect a targeted uncoating of its nucleocapsid at the nuclear pore.
引用
收藏
页码:E267 / E269
页数:3
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