CD2F-10: a new member of the CD2 subset of the immunoglobulin superfamily

被引:18
作者
Fennelly, JA
Tiwari, B
Davis, SJ
Evans, EJ [1 ]
机构
[1] Univ Oxford, Nuffield Dept Clin Med, Mol Sci Div, Oxford OX3 9DU, England
[2] Univ Oxford, Bioinformat Ctr, Sir William Dunn Sch Pathol, Oxford OX2 3RE, England
关键词
CD2F-10; CD2; subset; NK cells; T cells; human genome;
D O I
10.1007/s002510100364
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The CD2 subset of the immunoglobulin superfamily consists of a rapidly expanding family of leukocyte cell surface receptors, at least five of which (CD2, CD48, CD58, CD150, and CD244) are involved in lymphocyte activation as either receptors or ligands. Completion of the draft sequence of the human genome offers the possibility of systematically identifying the full set of proteins and interactions of this important family. Here we describe the identification and characterization of the first new member of the subset, CD2F-10, found exclusively by genome searching.
引用
收藏
页码:599 / 602
页数:4
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