Systematic genomic screen for tyrosine kinase mutations in CLL

被引:21
作者
Brown, J. R. [1 ,2 ]
Levine, R. L. [1 ,2 ,3 ]
Thompson, C. [1 ]
Basile, G. [1 ]
Gilliland, D. G. [1 ,2 ,3 ,4 ]
Freedman, A. S. [1 ,2 ]
机构
[1] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Dept Med, Boston, MA USA
[3] Brigham & Womens Hosp, Dept Med, Div Hematol, Boston, MA 02115 USA
[4] Howard Hughes Med Inst, Boston, MA 02115 USA
关键词
D O I
10.1038/leu.2008.222
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
[No abstract available]
引用
收藏
页码:1966 / 1969
页数:5
相关论文
共 8 条
[1]  
BROWN JR, 2008, BR J HEMATO IN PRESS
[2]   Genomic aberrations and survival in chronic lymphocytic leukemia. [J].
Döhner, H ;
Stilgenbauer, S ;
Benner, A ;
Leupolt, E ;
Kröber, A ;
Bullinger, L ;
Döhner, K ;
Bentz, M ;
Lichter, P .
NEW ENGLAND JOURNAL OF MEDICINE, 2000, 343 (26) :1910-1916
[3]   Patterns of somatic mutation in human cancer genomes [J].
Greenman, Christopher ;
Stephens, Philip ;
Smith, Raffaella ;
Dalgliesh, Gillian L. ;
Hunter, Christopher ;
Bignell, Graham ;
Davies, Helen ;
Teague, Jon ;
Butler, Adam ;
Edkins, Sarah ;
O'Meara, Sarah ;
Vastrik, Imre ;
Schmidt, Esther E. ;
Avis, Tim ;
Barthorpe, Syd ;
Bhamra, Gurpreet ;
Buck, Gemma ;
Choudhury, Bhudipa ;
Clements, Jody ;
Cole, Jennifer ;
Dicks, Ed ;
Forbes, Simon ;
Gray, Kris ;
Halliday, Kelly ;
Harrison, Rachel ;
Hills, Katy ;
Hinton, Jon ;
Jenkinson, Andy ;
Jones, David ;
Menzies, Andy ;
Mironenko, Tatiana ;
Perry, Janet ;
Raine, Keiran ;
Richardson, Dave ;
Shepherd, Rebecca ;
Small, Alexandra ;
Tofts, Calli ;
Varian, Jennifer ;
Webb, Tony ;
West, Sofie ;
Widaa, Sara ;
Yates, Andy ;
Cahill, Daniel P. ;
Louis, David N. ;
Goldstraw, Peter ;
Nicholson, Andrew G. ;
Brasseur, Francis ;
Looijenga, Leendert ;
Weber, Barbara L. ;
Chiew, Yoke-Eng .
NATURE, 2007, 446 (7132) :153-158
[4]   Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis [J].
Levine, RL ;
Wadleigh, M ;
Cools, J ;
Ebert, BL ;
Wernig, G ;
Huntly, BJP ;
Boggon, TJ ;
Wlodarska, L ;
Clark, JJ ;
Moore, S ;
Adelsperger, J ;
Koo, S ;
Lee, JC ;
Gabriel, S ;
Mercher, T ;
D'Andrea, A ;
Fröhling, S ;
Döhner, K ;
Marynen, P ;
Vandenberghe, P ;
Mesa, RA ;
Tefferi, A ;
Griffin, JD ;
Eck, MJ ;
Sellers, WR ;
Meyerson, M ;
Golub, TR ;
Lee, SJ ;
Gilliland, DG .
CANCER CELL, 2005, 7 (04) :387-397
[5]   High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia [J].
Loriaux, Marc M. ;
Levine, Ross L. ;
Tyner, Jeffrey W. ;
Froehling, Stefan ;
Scholl, Claudia ;
Stoffregen, Eric P. ;
Wernig, Gerlinde ;
Erickson, Heidi ;
Eide, Christopher A. ;
Berger, Roland ;
Bernard, Olivier A. ;
Griffin, James D. ;
Stone, Richard M. ;
Lee, Benjamin ;
Meyerson, Matthew ;
Heinrich, Michael C. ;
Deininger, Michael W. ;
Gilliland, D. Gary ;
Druker, Brian J. .
BLOOD, 2008, 111 (09) :4788-4796
[6]   EGFR mutations in lung cancer:: Correlation with clinical response to gefitinib therapy [J].
Paez, JG ;
Jänne, PA ;
Lee, JC ;
Tracy, S ;
Greulich, H ;
Gabriel, S ;
Herman, P ;
Kaye, FJ ;
Lindeman, N ;
Boggon, TJ ;
Naoki, K ;
Sasaki, H ;
Fujii, Y ;
Eck, MJ ;
Sellers, WR ;
Johnson, BE ;
Meyerson, M .
SCIENCE, 2004, 304 (5676) :1497-1500
[7]   ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia [J].
Rassenti, LZ ;
Huynh, L ;
Toy, TL ;
Chen, L ;
Keating, MJ ;
Gribben, JG ;
Neuberg, DS ;
Flinn, IW ;
Rai, KR ;
Byrd, JC ;
Kay, NE ;
Greaves, A ;
Weiss, A ;
Kipps, TJ .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (09) :893-901
[8]   Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia [J].
Tomasson, Michael H. ;
Xiang, Zhifu ;
Walgren, Richard ;
Zhao, Yu ;
Kasai, Yumi ;
Miner, Tracie ;
Ries, Rhonda E. ;
Lubman, Olga ;
Fremont, Daved H. ;
McLellan, Michael D. ;
Payton, Jacqueline E. ;
Westervelt, Peter ;
DiPersio, John F. ;
Link, Daniel C. ;
Walter, Matthew J. ;
Graubert, Timothy A. ;
Watson, Mark ;
Baty, Jack ;
Heath, Sharon ;
Shannon, William D. ;
Nagarajan, Rakesh ;
Bloomfield, Clara D. ;
Mardis, Elaine R. ;
Wilson, Richard K. ;
Ley, Timothy J. .
BLOOD, 2008, 111 (09) :4797-4808