Membrane curvature: How BAR domains bend bilayers

被引:149
作者
Zimmerberg, J [1 ]
McLaughlin, S
机构
[1] NICHHD, Lab Cellular & Mol Biophys, NIH, Bethesda, MD 20892 USA
[2] SUNY Stony Brook, Hlth Sci Ctr, Dept Physiol & Biophys, Stony Brook, NY 11794 USA
关键词
D O I
10.1016/j.cub.2004.02.060
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
An important new structure suggests the BAR domain is a membrane-binding module that can both produce and sense membrane curvature. BAR resembles a banana that binds membranes electrostatically through its positively charged, concave surface.
引用
收藏
页码:R250 / R252
页数:3
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