Protein translocation: Is Hsp70 pulling my chain?

被引:53
作者
Jensen, RE [1 ]
Johnson, AE
机构
[1] Johns Hopkins Univ, Sch Med, Dept Cell Biol & Anat, Baltimore, MD 21205 USA
[2] Texas A&M Univ, Hlth Sci Ctr, Dept Med Biochem & Genet, College Stn, TX 77843 USA
[3] Texas A&M Univ, Hlth Sci Ctr, Dept Chem, College Stn, TX 77843 USA
[4] Texas A&M Univ, Hlth Sci Ctr, Dept Biochem & Biophys, College Stn, TX 77843 USA
关键词
D O I
10.1016/S0960-9822(00)80012-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Hsp70 proteins in the lumen of the endoplasmic reticulum and in the mitochondrial matrix are thought to drive the translocation of proteins into each organelle. Recent experiments aimed at distinguishing between two models for Hsp70 function appear to reach opposite conclusions.
引用
收藏
页码:R779 / R782
页数:4
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