iPSCs to the Rescue in Alzheimer's Research

被引：21

作者：

Choi, Se Hoon ^{[1
]}

Tanzi, Rudolph E. ^{[1
]}

机构：

[1] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Genet & Aging Res Unit,Dept Neurol, Charlestown, MA 02129 USA

来源：

CELL STEM CELL | 2012年 / 10卷 / 03期

关键词：

PLURIPOTENT STEM-CELLS; DISEASE; GENE;

D O I：

10.1016/j.stem.2012.02.011

中图分类号：

Q813 [细胞工程];

学科分类号：

100113 [医学细胞生物学];

摘要：

A crucial limitation to our understanding of Alzheimer's disease has been the inability to test hypotheses on live, patient-specific neurons. A recent study in Nature by Israel et al. (2012) reports that iPSC-derived neurons from AD patients recapitulate multiple aspects of disease pathology.

引用

页码：235 / 236

页数：2

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