The impact of Toll-like receptors on bacterial virulence strategies

被引：20

作者：

Arpaia, Nicholas ^{[1
]}

Barton, Gregory M. ^{[2
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Program Immunol, New York, NY 10065 USA

[2] Univ Calif Berkeley, Dept Mol & Cell Biol, Div Immunol & Pathogenesis, Berkeley, CA 94720 USA

来源：

CURRENT OPINION IN MICROBIOLOGY | 2013年 / 16卷 / 01期

关键词：

NF-KAPPA-B; SALMONELLA-TYPHIMURIUM; SUPEROXIDE-DISMUTASE; PROTEIN; RECOGNITION; PHAGOCYTOSIS; MACROPHAGES; ACTIVATION; RESISTANCE; INHIBITION;

D O I：

10.1016/j.mib.2012.11.004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学];

摘要：

The mammalian immune system has evolved in the presence of microbes, both pathogenic and commensal. The consequences of microbial recognition by the host has led to the development of compensatory mechanisms by both the host and microbe to either resist or tolerate the existence of the other. In this review we discuss examples of this coevolutionary relationship. Because of space considerations and for conceptual clarity, we have focused on detection of bacteria by the Toll-like receptor (TLR) family and highlight examples of bacterial strategies to evade, subvert and in some cases even utilize these receptors.

引用

页码：17 / 22

页数：6

共 71 条

[1]

Drug Tolerance in Replicating Mycobacteria Mediated by a Macrophage-Induced Efflux Mechanism [J].

Adams, Kristin N. ;

Takaki, Kevin ;

Connolly, Lynn E. ;

Wiedenhoft, Heather ;

Winglee, Kathryn ;

Humbert, Olivier ;

Edelstein, Paul H. ;

Cosma, Christine L. ;

Ramakrishnan, Lalita .

CELL, 2011, 145 (01) :39-53

[2]

Ahmad-Nejad P, 2002, EUR J IMMUNOL, V32, P1958, DOI 10.1002/1521-4141(200207)32:7<1958::AID-IMMU1958>3.0.CO

[3]

2-U

[4]

Evasion of Toll-like receptor 5 by flagellated bacteria [J].

Andersen-Nissen, E ;

Smith, KD ;

Strobe, KL ;

Barrett, SLR ;

Cookson, BT ;

Logan, SM ;

Aderem, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (26) :9247-9252

[5]

PHAGOSOME-LYSOSOME INTERACTIONS IN CULTURED MACROPHAGES INFECTED WITH VIRULENT TUBERCLE-BACILLI - REVERSAL OF USUAL NONFUSION PATTERN AND OBSERVATIONS ON BACTERIAL SURVIVAL [J].

ARMSTRONG, JA ;

HART, PD .

JOURNAL OF EXPERIMENTAL MEDICINE, 1975, 142 (01) :1-16

[6]

TLR Signaling Is Required for Salmonella typhimurium Virulence [J].

Arpaia, Nicholas ;

Godec, Jernej ;

Lau, Laura ;

Sivick, Kelsey E. ;

McLaughlin, Laura M. ;

Jones, Marcus B. ;

Dracheva, Tatiana ;

Peterson, Scott N. ;

Monack, Denise M. ;

Barton, Gregory M. .

CELL, 2011, 144 (05) :675-688

[7]

A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKγ to dampen the host NF-κB-mediated inflammatory response [J].

Ashida, Hiroshi ;

Kim, Minsoo ;

Schmidt-Supprian, Marc ;

Ma, Averil ;

Ogawa, Michinaga ;

Sasakawa, Chihiro .

NATURE CELL BIOLOGY, 2010, 12 (01) :66-U164

[8]

Recognition of antimicrobial peptides by a bacterial sensor kinase [J].

Bader, MW ;

Sanowar, S ;

Daley, ME ;

Schneider, AR ;

Cho, US ;

Xu, WQ ;

Klevit, RE ;

Le Moual, H ;

Miller, S .

CELL, 2005, 122 (03) :461-472

[9]

Nucleic Acid Recognition by the Innate Immune System [J].

Barbalat, Roman ;

Ewald, Sarah E. ;

Mouchess, Maria L. ;

Barton, Gregory M. .

ANNUAL REVIEW OF IMMUNOLOGY, VOL 29, 2011, 29 :185-214

[10]

A cell biological view of Toll-like receptor function: regulation through compartmentalization [J].

Barton, Gregory M. ;

Kagan, Jonathan C. .

NATURE REVIEWS IMMUNOLOGY, 2009, 9 (08) :535-542

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