Nitrile- and amide-converting microbial enzymes:: Stereo-, regio- and chemoselectivity

被引：115

作者：

Martínková, L ^{[1
]}

Kren, V ^{[1
]}

机构：

[1] Acad Sci Czech Republ, Inst Microbiol, Lab Biotransformat, CZ-14220 Prague 4, Czech Republic

来源：

BIOCATALYSIS AND BIOTRANSFORMATION | 2002年 / 20卷 / 02期

关键词：

nitrile hydratase; nitrilase; amidase; aminoacylase; carbamoylase; deacetylase;

D O I：

10.1080/10242420290018069

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Biotransformations using microbial nitrile- and amide-converting enzymes have developed considerably in the recent years. Most processes profited from the stereo-, regio- and chemoselectivity of nitrile hydratases, nitrilases and amidases specific for primary or secondary amides. The aim of this review is to discuss the developments in this branch of biotransformations in the last ca. 5 years by taking highlights from research journals, patents and industrial applications.

引用

页码：73 / 93

页数：21

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