Psoriatic arthritis: therapeutic principles

被引:7
作者
Feuchtenberger, Martin [1 ]
Kleinert, Stefan [1 ]
Tony, Hans-Peter [1 ]
Kneitz, Christian [1 ]
机构
[1] Univ Wurzburg, Dept Rheumatol & Clin Immunol, Med Klin & Poliklin 2, D-97070 Wurzburg, Germany
关键词
D O I
10.1016/j.clindermatol.2007.11.005
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
From the dermatologic point of view, psoriatic arthritis (PsA) was seen for a long time as a rare complication of psoriasis. Recent Studies, however, reveal a high prevalence of PsA among patients with psoriasis, and the impact of PsA due to Chronic inflammation of peripheral joints, axial joints, and periarticular structures leading to radiologic progression, functional impairment, and reduction in quality of life is well recognized. Substantial improvement in understanding immunopathology of PsA has led to a variety of new therapeutic Options. This article reviews the current therapeutic principles for PsA. (c) 2008 Elsevier Inc. All rights reserved.
引用
收藏
页码:460 / 463
页数:4
相关论文
共 20 条
[1]  
ABUSHAKRA M, 1995, J RHEUMATOL, V22, P241
[2]   A randomised, double blind, placebo controlled, multicentre trial of combination therapy with methotrexate plus ciclosporin in patients with active psoriatic arthritis [J].
Fraser, AD ;
van Kuijk, AWR ;
Westhovens, R ;
Karim, Z ;
Wakefield, R ;
Gerards, AH ;
Landewé, R ;
Steinfeld, SD ;
Emery, P ;
Dijkmans, BAC ;
Veale, DJ .
ANNALS OF THE RHEUMATIC DISEASES, 2005, 64 (06) :859-864
[3]   Adalimumab improves joint-related and skin-related functional impairment in patients with psoriatic arthritis: patient-reported outcomes of the Adalimumab Effectiveness in Psoriatic Arthritis Trial [J].
Gladman, D. D. ;
Mease, P. J. ;
Cifaldi, M. A. ;
Perdok, R. J. ;
Sasso, E. ;
Medich, J. .
ANNALS OF THE RHEUMATIC DISEASES, 2007, 66 (02) :163-168
[4]   Psoriatic arthritis: epidemiology, clinical features, course, and outcome [J].
Gladman, DD ;
Antoni, C ;
Mease, P ;
Clegg, DO ;
Nash, P .
ANNALS OF THE RHEUMATIC DISEASES, 2005, 64 :14-17
[5]  
Gladman DD, 1998, J RHEUMATOL, V25, P730
[6]  
GLADMAN DD, 1986, J RHEUMATOL, V13, P586
[7]  
JONES G, COCHRANE DATABASE SY, V3, DOI SICI C13000212
[8]   Efficacy and safety of leflunomide in the treatment of psoriatic arthritis and psoriasis - A multinational, double-blind, randomized, placebo-controlled clinical trial [J].
Kaltwasser, JP ;
Nash, P ;
Gladman, D ;
Rosen, CF ;
Behrens, F ;
Jones, P ;
Wollenhaupt, J ;
Falk, FG ;
Mease, P .
ARTHRITIS AND RHEUMATISM, 2004, 50 (06) :1939-1950
[9]   The infliximab multinational psoriatic arthritis controlled trial (IMPACT): results of radiographic analyses after 1 year [J].
Kavanaugh, A. ;
Antoni, C. E. ;
Gladman, D. ;
Wassenberg, S. ;
Zhou, B. ;
Beutler, A. ;
Keenan, G. ;
Burmester, G. ;
Furst, D. E. ;
Weisman, M. H. ;
Kalden, J. R. ;
Smolen, J. ;
van der Heijde, D. .
ANNALS OF THE RHEUMATIC DISEASES, 2006, 65 (08) :1038-1043
[10]  
Kavanaugh A, 2006, CURR OPIN RHEUMATOL, V18, P347