SPECT and PET in the evaluation of coronary artery disease

被引:21
作者
Jadvar, H
Strauss, HW
Segall, GM [1 ]
机构
[1] Stanford Univ, Sch Med, Dept Radiol, Div Nucl Med, Stanford, CA 94305 USA
[2] VA Palo Alto Hlth Care Syst, Nucl Med Serv, Stanford, CA 94305 USA
关键词
coronary vessels; diseases; emission CT (ECT); radionuclide studies; myocardium;
D O I
10.1148/radiographics.19.4.g99jl08915
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Cardiac positron emission tomography (PET) is an accurate method for assessing myocardial perfusion and metabolism in the evaluation of coronary heart disease. PET allows more accurate detection of myocardial ischemia than single photon emission tomography (SPECT). In addition, PET has higher spatial resolution and allows attenuation correction and the quantification of various physiologic parameters. PET with 2-(fluorine-18) fluoro-2-deoxy-D-glucose is considered the standard of reference for predicting improvement in regional or global left ventricular function after revascularization by identifying hibernating viable myocardium that shows diminished perfusion and preserved metabolism. Other less commonly used clinical applications of cardiac PET include assessment of myocardial oxygen consumption and fatty acid metabolism. The use of PET in myocardial imaging is expected to increase in the near future with the regional distribution of positron-emitting radiotracers and the emergence of relatively low-cost PET systems.
引用
收藏
页码:915 / 926
页数:12
相关论文
共 60 条
[1]  
ALTEHOEFER C, 1992, EUR J NUCL MED, V19, P334
[2]   Cardiac F-18-FDG-SPET studies in patients with non-insulin-dependent diabetes mellitus during hyperinsulinaemic euglycaemic clamping [J].
Bax, JJ ;
Visser, FC ;
Raymakers, PGHM ;
VanLingen, A ;
Cornel, JH ;
Huitink, JM ;
Elhendy, A ;
Heine, RJ ;
Visser, CA .
NUCLEAR MEDICINE COMMUNICATIONS, 1997, 18 (03) :200-206
[3]  
Bergmann S R, 1994, Am J Card Imaging, V8, P181
[4]  
BERRY JJ, 1991, J NUCL MED, V32, P1518
[5]   IDENTIFICATION OF VIABLE MYOCARDIUM IN PATIENTS WITH CHRONIC CORONARY-ARTERY DISEASE AND LEFT-VENTRICULAR DYSFUNCTION - COMPARISON OF THALLIUM SCINTIGRAPHY WITH REINJECTION AND PET IMAGING WITH F-18 FLUORODEOXYGLUCOSE [J].
BONOW, RO ;
DILSIZIAN, V ;
CUOCOLO, A ;
BACHARACH, SL .
CIRCULATION, 1991, 83 (01) :26-37
[6]   Identification of viable myocardium [J].
Bonow, RO .
CIRCULATION, 1996, 94 (11) :2674-2680
[7]   THE STUNNED MYOCARDIUM - PROLONGED, POST-ISCHEMIC VENTRICULAR DYSFUNCTION [J].
BRAUNWALD, E ;
KLONER, RA .
CIRCULATION, 1982, 66 (06) :1146-1149
[8]   Prognostic value of myocardial perfusion imaging: State of the art and new developments [J].
Brown, KA .
JOURNAL OF NUCLEAR CARDIOLOGY, 1996, 3 (06) :516-537
[9]   POSITRON EMISSION TOMOGRAPHY DETECTS METABOLIC VIABILITY IN MYOCARDIUM WITH PERSISTENT 24-HOUR SINGLE-PHOTON EMISSION COMPUTED-TOMOGRAPHY TL-201 DEFECTS [J].
BRUNKEN, RC ;
MODY, FV ;
HAWKINS, RA ;
NIENABER, C ;
PHELPS, ME ;
SCHELBERT, HR .
CIRCULATION, 1992, 86 (05) :1357-1369
[10]  
BURT RW, 1995, J NUCL MED, V36, P176