Soluble polymer-supported synthesis of isoxazoles

被引：57

作者：

Shang, YJ ^{[1
]}

Wang, YG ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310027, Peoples R China

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 12期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/S0040-4039(02)00185-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first soluble polymer-supported synthesis of isoxazoles through a 1,3-dipolar cycloaddition is described. A soluble polymer-supported alkyne reacts with nitrile oxides generated in situ to give isoxazoles in good yield. (C) 2002 Published by Elsevier Science Ltd.

引用

页码：2247 / 2249

页数：3

共 6 条

[1] Organic synthesis on soluble polymer supports: Liquid-phase methodologies [J].

Gravert, DJ ;

Janda, KD .

CHEMICAL REVIEWS, 1997, 97 (02) :489-509

[2] Solution-phase combinatorial synthesis of isoxazolines and isoxazoles using [2+3] cycloaddition reaction of nitrile oxides [J].

Kang, KH ;

Pae, AN ;

Choi, KI ;

Cho, YS ;

Chung, BY ;

Lee, JE ;

Jung, SH ;

Koh, HY ;

Lee, HY .

TETRAHEDRON LETTERS, 2001, 42 (06) :1057-1060

[3] THE ISOXAZOLINE ROUTE TO THE MOLECULES OF NATURE [J].

KOZIKOWSKI, AP .

ACCOUNTS OF CHEMICAL RESEARCH, 1984, 17 (12) :410-416

[4]

LARSEN KE, 1984, TETRAHEDRON, V40, P2985

[5] THE NITRILE OXIDE ISOXAZOLINE ROUTE TO HIGHER-CARBON DIALDOSES [J].

PATON, RM ;

YOUNG, AA .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1994, (08) :993-994

[6] One pot solid phase synthesis of isoxazolines [J].

Shankar, BB ;

Yang, DY ;

Girton, S ;

Ganguly, AK .

TETRAHEDRON LETTERS, 1998, 39 (17) :2447-2448

← 1 →