Clinical Discussion and Review of the Management of Brain Metastases

被引：45

作者：

Brastianos, Priscilla K. ^{[1
]}

Curry, William T. ^{[2
]}

Oh, Kevin S. ^{[3
]}

机构：

[1] Massachusetts Gen Hosp, Dept Med, Div Hematol Oncol, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Dept Neurosurg, Boston, MA 02114 USA

[3] Massachusetts Gen Hosp, Dept Radiat Oncol, Boston, MA 02114 USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2013年 / 11卷 / 09期

关键词：

CELL LUNG-CANCER; NERVOUS-SYSTEM METASTASES; THERAPY-ONCOLOGY-GROUP; PHASE-II TRIAL; POSTOPERATIVE RESECTION CAVITY; RANDOMIZED CONTROLLED-TRIAL; RADIATION-THERAPY; BREAST-CANCER; STEREOTACTIC RADIOSURGERY; CEREBRAL METASTASES;

D O I：

10.6004/jnccn.2013.0133

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Brain metastases are common in patients with cancer and are associated with a poor prognosis. Optimal treatment requires an integrative multidisciplinary approach, and therapeutic options may include stereotactic radiosurgery, whole-brain radiation therapy, surgical resection, chemotherapy, and targeted agents. The goals of therapy are to prolong survival, preserve neurologic function, and palliate symptoms. This article outlines the various therapeutic modalities, factors that guide treatment decisions, and medical management of frequently encountered complications of brain metastases.

引用

页码：1153 / 1164

页数：12

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