Killing the messenger: new insights into nonsense-mediated mRNA decay

被引:128
作者
Byers, PH
机构
[1] Univ Washington, Dept Pathol, Seattle, WA 98195 USA
[2] Univ Washington, Dept Med, Seattle, WA 98195 USA
关键词
D O I
10.1172/JCI200214841
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
引用
收藏
页码:3 / 6
页数:4
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共 20 条
  • [1] EVIDENCE TO IMPLICATE TRANSLATION BY RIBOSOMES IN THE MECHANISM BY WHICH NONSENSE CODONS REDUCE THE NUCLEAR-LEVEL OF HUMAN TRIOSEPHOSPHATE ISOMERASE MESSENGER-RNA
    BELGRADER, P
    CHENG, J
    MAQUAT, LE
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (02) : 482 - 486
  • [2] Characterization of the biochemical properties of the human Upf1 gene product that is involved in nonsense-mediated mRNA decay
    Bhattacharya, A
    Czaplinski, K
    Trifillis, P
    He, F
    Jacobson, A
    Peltz, SW
    [J]. RNA, 2000, 6 (09) : 1226 - 1235
  • [3] A coactivator of pre-mRNA splicing
    Blencowe, BJ
    Issner, R
    Nickerson, JA
    Sharp, PA
    [J]. GENES & DEVELOPMENT, 1998, 12 (07) : 996 - 1009
  • [4] A splicing-dependent regulatory mechanism that detects translation signals
    Carter, MS
    Li, SL
    Wilkinson, MF
    [J]. EMBO JOURNAL, 1996, 15 (21) : 5965 - 5975
  • [5] A REGULATORY MECHANISM THAT DETECTS PREMATURE NONSENSE CODONS IN T-CELL RECEPTOR TRANSCRIPTS IN-VIVO IS REVERSED BY PROTEIN-SYNTHESIS INHIBITORS IN-VITRO
    CARTER, MS
    DOSKOW, J
    MORRIS, P
    LI, SL
    NHIM, RP
    SANDSTEDT, S
    WILKINSON, MF
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (48) : 28995 - 29003
  • [6] INTRONS ARE CIS EFFECTORS OF THE NONSENSE-CODON-MEDIATED REDUCTION IN NUCLEAR MESSENGER-RNA ABUNDANCE
    CHENG, J
    BELGRADER, P
    ZHOU, XB
    MAQUAT, LE
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 1994, 14 (09) : 6317 - 6325
  • [7] Coupled transcription and translation within nuclei of mammalian cells
    Iborra, FJ
    Jackson, DA
    Cook, PR
    [J]. SCIENCE, 2001, 293 (5532) : 1139 - 1142
  • [8] Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20
    Ishigaki, Y
    Li, XJ
    Serin, G
    Maquat, LE
    [J]. CELL, 2001, 106 (05) : 607 - 617
  • [9] Tracking COL1A1 RNA in osteogenesis imperfecta: Splice-defective transcripts initiate transport from the gene but are retained within the SC35 domain
    Johnson, C
    Primorac, D
    McKinstry, M
    McNeil, J
    Rowe, D
    Lawrence, JB
    [J]. JOURNAL OF CELL BIOLOGY, 2000, 150 (03) : 417 - 431
  • [10] Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex
    Kataoka, N
    Diem, MD
    Kim, VN
    Yong, J
    Dreyfuss, G
    [J]. EMBO JOURNAL, 2001, 20 (22) : 6424 - 6433