The influence of ligand bite angle on the enantioselectivity of copper(II)-catalysed Diels-Alder reactions

被引：92

作者：

Davies, IW ^{[1
]}

Gerena, L ^{[1
]}

Castonguay, L ^{[1
]}

Senanayake, CH ^{[1
]}

Larsen, RD ^{[1
]}

Verhoeven, TR ^{[1
]}

Reider, PJ ^{[1
]}

机构：

[1] MERCK & CO INC,DEPT MOL DESIGN & DIVERS,RAHWAY,NJ

来源：

CHEMICAL COMMUNICATIONS | 1996年 / 15期

关键词：

D O I：

10.1039/cc9960001753

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Novel spirobis(oxazolines) provide excellent levels of stereocontrol in copper-catalysed Diels-Alder reactions; the larger the ligand bite angle the higher the enantioselection (up to 98.4% ee).

引用

页码：1753 / 1754

页数：2

共 10 条

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