Synthesis and characterization of dextran-based hydrogel prepared by photocrosslinking

被引：78

作者：

Kim, SH ^{[1
]}

Won, CY ^{[1
]}

Chu, CC ^{[1
]}

机构：

[1] Cornell Univ, Dept Text & Apparel, Biomed Engn Program, Fiber & Polymer Sci Program, Ithaca, NY 14853 USA

来源：

CARBOHYDRATE POLYMERS | 1999年 / 40卷 / 03期

关键词：

hydrogel; dextran; bromoacetyl bromide; swelling;

D O I：

10.1016/S0144-8617(99)00053-3

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A polysaccharide-based hydrogel was prepared by photocrosslinking of modified dextran. Dextran was first bromoacetylated by bromoacetyl bromide and was subsequently reacted with sodium acrylate for incorporating a vinyl group. The acrylated dextran was then irradiated by a long-wave UV lamp for photocrosslinking. Reaction products (bromoacetyl dextran, acrylated dextran, and hydrogel) were characterized by elemental analysis, FT-IR, H-1-NMR, and C-13-NMR. The prepared dextran hydrogels showed a wide range of swelling behavior in different pH media, depending on the degree of substitution in bromoacetyl dextrans. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：183 / 190

页数：8

共 22 条

[1] ANDREOPOULOS FM, 1996, J AM CHEM SOC, V118, P6230
[2] BELL C, 1994, BIOMATERIALS DRUG CE
[3] THE INVITRO DEGRADATION OF POLY(GLYCOLIC ACID) SUTURES - EFFECT OF PH
CHU, CC
[J]. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1981, 15 (06): : 795 - 804
[4] Chu CC, 1997, Wound Closure Biomaterials andDevices, DOI DOI 10.1021/la900298m
[5] DAGANI R, 1997, CHEM ENG NEWS, P26
[6] Synthesis and characterization of photo-gross-linked polymers based on poly(L-lactic acid-co-L-aspartic acid)
Elisseeff, J
Anseth, K
Langer, R
Hrkach, JS
[J]. MACROMOLECULES, 1997, 30 (07) : 2182 - 2184
[7] Li Y, 1997, J APPL POLYM SCI, V63, P1173, DOI 10.1002/(SICI)1097-4628(19970228)63:9<1173::AID-APP9>3.0.CO
[8] 2-E
[9] MORA M, 1990, MAKROMOL CHEM, V191, P1051
[10] NAGASAKI Y, 1997, CHEMTECH MAR, P23

← 1 2 3 →