Efficient synthesis of pyrrolizidine and indolizidine derivatives using nickel-catalyzed cyclization of 1,3-diene and aldehyde: Formal total synthesis of (-)-elaeokanine C

被引：42

作者：

Sato, Y

Saito, N

Mori, M

机构：

[1] Faculty of Pharmaceutical Sciences, Hokkaido University

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 22期

关键词：

D O I：

10.1016/S0040-4039(97)00782-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Pyrrolizidine and indolizidine skeletons were successfully constructed by nickel-catalyzed cyclization of 1,3-diene and aldehyde in a chain. A formal total synthesis of an Elaeocarpus alkaloid, (-)-Elaeokanine C, in the naturally occurring form was achieved using this cyclization, (C) 1997 Elsevier Science Ltd.

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页码：3931 / 3934

页数：4

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