Absorbed doses to patients from 191Pt-;193mPt- and 195mPt-cisplatin

被引：11

作者：

Areberg, J ^{[1
]}

Norrgren, K ^{[1
]}

Mattsson, S ^{[1
]}

机构：

[1] Malmo Univ Hosp, Dept Radiat Phys, SE-20502 Malmo, Sweden

来源：

APPLIED RADIATION AND ISOTOPES | 1999年 / 51卷 / 05期

关键词：

D O I：

10.1016/S0969-8043(99)00082-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Cisplatin, a chemotherapeutic drug, can be synthesized using radioactive platinum and then used for pharmacokinetic studies and tumor imaging. We have calculated the absorbed doses to various organs and tissues as well as the effective doses from Pt-191-, Pt-193m- and Pt-195m-cisplatin after administration to humans for diagnostic purposes. Liver was the organ that received the highest absorbed dose. The effective dose from Pt-191-, Pt-193m- and Pt-195m-cisplatin was 0.10 +/- 0.02, 0.17 +/- 0.04 and 0.23 +/- 0.05 mSv/MBq respectively. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：581 / 586

页数：6

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