Using Light to Reinstate Respiratory Plasticity

被引：2

作者：

Arenkiel, Benjamin R. ^{[1
,2
]}

Peca, Joao ^{[1
,3
]}

机构：

[1] Duke Univ, Med Ctr, Dept Neurobiol, Durham, NC 27710 USA

[2] Howard Hughes Med Inst, Chevy Chase, MD USA

[3] Univ Coimbra, Ctr Neurosci & Cell Biol, PhD Programme Expt Biol & Biomed, Coimbra, Portugal

来源：

JOURNAL OF NEUROPHYSIOLOGY | 2009年 / 101卷 / 04期

关键词：

SPINAL-CORD-INJURY; RETINAL DEGENERATION; ECTOPIC EXPRESSION; VISUAL FUNCTION; MICE; CHANNELRHODOPSIN-2; RESTORATION; STIMULATION; NEURONS; CHANNEL;

D O I：

10.1152/jn.00009.2009

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Arenkiel BR, Peca J. Using light to reinstate respiratory plasticity. J Neurophysiol 101: 1695-1698, 2009. First published February 18, 2009; doi: 10.1152/jn.00009.2009. Restoring normal function to damaged or diseased nervous tissue remains a major goal of both basic and clinical neuroscience research. Advances in genetic technologies now allow targeted control of neuronal activity in the mammalian nervous system, providing novel therapeutic avenues to repair or bypass faulty circuits. Here we review recent work published in the Journal of Neuroscience by Alilain et al., demonstrating the use of Channelrhodopsin-2 to restore breathing in rodent models of spinal cord injury.

引用

页码：1695 / 1698

页数：4

共 16 条

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