Veterans aging cohort three-site study (VACS 3): overview and description

被引:29
作者
Smola, S
Justice, AC [1 ]
Wagner, J
Rabeneck, L
Weissman, S
Rodriguez-Barradas, M
机构
[1] Univ Pittsburgh, Sch Med, VACS Ctr, Div Gen Internal Med, Pittsburgh, PA 15260 USA
[2] VA Pittsburgh Healthcare Syst, Ctr Hlth Equ Res & Promot, Pittsburgh, PA 15240 USA
[3] Baylor Coll Med, Dept Med, Houston, TX 77030 USA
[4] VA Med Ctr, Houston, TX USA
关键词
Veterans Aging Cohort Three-Site Study; middle-aged individuals; HIV infection; age-related differences;
D O I
10.1016/S0895-4356(01)00448-6
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Outcomes for middle-aged and older individuals with HIN infection are poor, and are likely to be mediated by age-related differences in risks and resources (access to care, relationship with the provider, comorbid conditions, health habits, and changes brought about by aging). The goal of the Veterans Aging Cohort Three-Site Study (VACS 3) is to study the influence of age and mediating factors on outcomes with HIV in order to identify mutable mediators of poorer outcomes. VACS 3 is an observational, longitudinal study. Data sources include patient and provider surveys and electronic medical data collected at baseline and 12-month follow-up from the Infections Disease Clinics at three Veterans Affairs Medical Centers (Cleveland, OH, Houston, TX, and Manhattan, NY). Trained Survey Coordinators at each site determined which patients are HIV infected, obtained consent, and asked the patient to complete a questionnaire. The primary provider also completed a questionnaire. Twelve-month follow-up will be completed July 2001. Of all veterans with HIV seen in these clinics 85% (881) have consented and enrolled. Of the 881 corresponding provider surveys, 92% were completed. Mean age is 49; 55% are African-American; 38% of the sample were men who have sex with men; and less than 2% are women. Almost a third (32%) have been without a permanent address. Complimentary or alternative therapies are common as are the use of cigarettes, alcohol, and illicit drugs. The majority (87%) of the patients are taking multiple antiretroviral medications. The median CD4 count is 331 mm(3), and the median viral load was 714 copies/ml. There is substantial variation by site. Veterans with HIV infection have characteristics that will likely become more prevalent among HIN-infected persons in the United States: they are older, commonly suffer comorbid disease, and are members of minority populations. VACS 3 may help inform the design of future clinical interventions to improve outcomes for people aging with HIV. (C) 2001 Elsevier Science Inc. All rights reserved.
引用
收藏
页码:S61 / S76
页数:16
相关论文
共 27 条
[1]   SCREENING FOR DEPRESSION IN WELL OLDER ADULTS - EVALUATION OF A SHORT-FORM OF THE CES-D [J].
ANDRESEN, EM ;
MALMGREN, JA ;
CARTER, WB ;
PATRICK, DL .
AMERICAN JOURNAL OF PREVENTIVE MEDICINE, 1994, 10 (02) :77-84
[2]  
BABOR TF, 1989, AUDIT ALCOHOL USE DI
[3]   Comparative responsiveness of generic versus disease-specific and weighted versus unweighted health status measures in carpal tunnel syndrome [J].
Bessette, L ;
Sangha, O ;
Kuntz, KM ;
Keller, RB ;
Lew, RA ;
Fossel, AH ;
Katz, JN .
MEDICAL CARE, 1998, 36 (04) :491-502
[4]  
*CARD SOFTW, 1998, TEL STAND US GUID
[5]  
*CDC, 1987, HIV AIDS SURVEILLANC, V9, P1
[6]   A NEW METHOD OF CLASSIFYING PROGNOSTIC CO-MORBIDITY IN LONGITUDINAL-STUDIES - DEVELOPMENT AND VALIDATION [J].
CHARLSON, ME ;
POMPEI, P ;
ALES, KL ;
MACKENZIE, CR .
JOURNAL OF CHRONIC DISEASES, 1987, 40 (05) :373-383
[7]   Self-reported adherence to antiretroviral medications among participants in HIV clinical trials: the AACTG Adherence Instruments [J].
Chesney, MA ;
Ickovics, JR ;
Chambers, DB ;
Gifford, AL ;
Neidig, J ;
Zwickl, B ;
Wu, AW .
AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV, 2000, 12 (03) :255-266
[8]   THE SATISFACTION WITH LIFE SCALE [J].
DIENER, E ;
EMMONS, RA ;
LARSEN, RJ ;
GRIFFIN, S .
JOURNAL OF PERSONALITY ASSESSMENT, 1985, 49 (01) :71-75
[9]   MORTALITY ASCERTAINMENT IN THE VETERAN POPULATION - ALTERNATIVES TO THE NATIONAL DEATH INDEX [J].
FISHER, SG ;
WEBER, L ;
GOLDBERG, J ;
DAVIS, F .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1995, 141 (03) :242-250
[10]   The association of attributes of primary care with the delivery of clinical preventive services [J].
Flocke, SA ;
Stange, KC ;
Zyzanski, SJ .
MEDICAL CARE, 1998, 36 (08) :AS21-AS30