Functionalized copolymers and their composites with polylactide and hydroxyapatite

被引:25
作者
Jin, S
Gonsalves, KE [1 ]
机构
[1] Univ Connecticut, Inst Mat Sci, Dept Chem, Storrs, CT 06269 USA
[2] Univ Connecticut, Inst Mat Sci, Polymer Program, Storrs, CT 06269 USA
关键词
D O I
10.1023/A:1026425824686
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Synthetic copolymers poly(epsilon-caprolactone-co-vinylphosphonic acid) (P(MDOVPA) and poly(epsilon-caprolactone-co-dimethylvinylphosphoester) (P(MDOVPE)) were used to prepare composites with polylactide (PLac) and hydroxyapatite (HAp). The P(MDOVPA) is used as filler in PLac films, as it has pendant functional groups P(O)(OH)(2), providing nucleation sites for the deposition of HAp in simulated body fluid. HAp growth on P(MDOVPA) powder and PLac-P(MDOVPA) film was observed by Fourier transform infrared spectroscopy (FTIR), energy dispersive X-ray analysis (EDX) and X-ray diffraction (XRD). P(MDOVPE) and PLac blend are miscible, and the incorporation of hydrophilic P(MDOVPA) into PLac increased the hydrophilicity of the blend. Synthetic HAp was used to make multilayered, alternating organic-inorganic composites with porous PLac-P(MDOVPE) blends. (C) 1999 Kluwer Academic Publishers.
引用
收藏
页码:363 / 368
页数:6
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