Is CD46 the cellular receptor for measles virus?

被引:55
作者
Buckland, R
Wild, TF
机构
[1] Inst. Natl. de la S. et de la Rech., Immunité et Vaccination, Institut Pasteur de Lyon
关键词
MV receptor; CD46; vaccine;
D O I
10.1016/S0168-1702(96)01421-9
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Although CD46 would appear to be the cellular receptor for vaccine strains of measles virus (MV), recently there has been an accumulation of data suggesting that CD46 does not play this role for MV wild-type strains. Clarification of the nature of the MV receptor is necessary for the development of more effective vaccines against this virus which is responsible for the deaths of nearly two million children each year in the Third World. (C) 1997 Elsevier Science B.V.
引用
收藏
页码:1 / 9
页数:9
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