Licorice preparations improve efficiency of chemotherapy and surgical treatment of transplanted tumors

被引：11

作者：

Gol'dberg, E. D. ^{[1
]}

Amosova, E. N. ^{[1
]}

Zueva, E. P. ^{[1
]}

Razina, T. G. ^{[1
]}

Krylova, S. G. ^{[1
]}

Zorikov, P. S. ^{[2
]}

机构：

[1] Russian Acad Med Sci, Siberian Div, Tomsk Res Ctr, Inst Pharmacol, Tomsk 109801, Russia

[2] Russian Acad Sci, Far Eastern Div, VL Komarov Mt Taiga Stn, Moscow 117901, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2008年 / 145卷 / 02期

关键词：

transplanted tumors; licorice extract; glyciram;

D O I：

10.1007/s10517-008-0063-0

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Experiments on animals with Lewis lung carcinoma and Ehrlich tumor showed that licorice (glycyrrhiza) extract and glyciram prepared from this plant improved the antitumor effect of cyclophosphamide. Glyciram reduced the toxic effect of the cytostatic on peripheral blood leukocytes. Licorice extract inhibited the growth of Ehrlich tumor and development of metastases in mice with Lewis lung carcinoma. Glyciram administered to mice after removal of Lewis lung carcinoma produced an antimetastatic effect and prevented relapses.

引用

页码：252 / 255

页数：4

共 10 条

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