Comparative Evaluation of the Nanosphere Verigene RV plus Assay and the Simplexa Flu A/B & RSV Kit for Detection of Influenza and Respiratory Syncytial Viruses

被引：39

作者：

Alby, Kevin ^{[1
]}

Popowitch, Elena B. ^{[1
]}

Miller, Melissa B. ^{[1
,2
]}

机构：

[1] UNC Hlth Care, Clin Microbiol Immunol Labs, Chapel Hill, NC USA

[2] UNC Sch Med, Dept Pathol & Lab Med, Chapel Hill, NC USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2013年 / 51卷 / 01期

关键词：

D O I：

10.1128/JCM.02504-12

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Using retrospective (n = 200) and prospective (n = 150) nasopharyngeal specimens, we evaluated the Nanosphere Verigene RV+ and the Focus Diagnostics Simplexa Flu A/B & RSV tests. Overall, RV+ demonstrated sensitivities and specificities of 96.6% and 100% for influenza A virus, 100% and 99.7% for influenza B virus, and 100% and 100% for respiratory syncytial virus (RSV), while the Simplexa test sensitivities and specificities were 82.8 and 99.7%, 76.2 and 100%, and 94.6 and 100%, respectively.

引用

页码：352 / 353

页数：2

共 5 条

[1] Clinical performance of the 3M Rapid Detection Flu A plus B Test compared to R-Mix culture, DFA and BinaxNOW Influenza A&B Test [J].

Ginocchio, Christine C. ;

Lotlikar, Madhavi ;

Falk, Leon ;

Arora, Suman ;

Kowerska, Margaret ;

Bornfreund, Mark ;

Manji, Ryhana .

JOURNAL OF CLINICAL VIROLOGY, 2009, 45 (02) :146-149

[2] Real-Time Detection of Influenza A, Influenza B, and Respiratory Syncytial Virus A and B in Respiratory Specimens by Use of Nanoparticle Probes [J].

Jannetto, Paul J. ;

Buchan, Blake W. ;

Vaughan, Kimberly A. ;

Ledford, Joellen S. ;

Anderson, Dennis K. ;

Henley, Donald C. ;

Quigley, Neil B. ;

Ledeboer, Nathan A. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2010, 48 (11) :3997-4002

[3] Performance of a rapid antigen test (Binax NOW® RSV) for diagnosis of respiratory syncytial virus compared with real-time polymerase chain reaction in a pediatric population [J].

Miernyk, Karen ;

Bulkow, Lisa ;

DeByle, Carolynn ;

Chikoyak, Lori ;

Hummel, Kimberlee Boyd ;

Hennessy, Thomas ;

Singleton, Rosalyn .

JOURNAL OF CLINICAL VIROLOGY, 2011, 50 (03) :240-243

[4] Retrospective and Prospective Verification of the Cepheid Xpert Influenza Virus Assay [J].

Popowitch, Elena B. ;

Rogers, Elaine ;

Miller, Melissa B. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2011, 49 (09) :3368-3369

[5] Applicability of a real-time quantitative PCR assay for diagnosis of respiratory syncytial virus infection in immunocompromised adults [J].

van Elden, LJR ;

van Loon, AM ;

van der Beek, A ;

Hendriksen, KAW ;

Hoepelman, AIM ;

van Kraaij, MGJ ;

Schipper, P ;

Nijhuis, M .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (09) :4378-4381

← 1 →