Formation of the lignan (+)-secoisolariciresinol by cell-free extracts of Arctium lappa

被引：22

作者：

Umezawa, T

Shimada, M

机构：

[1] Wood Research Institute, Kyoto University, Kyoto, 593, Uji

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1996年 / 60卷 / 04期

关键词：

Arctium lappa; (+)-secoisolariciresinol; enantioselective; lignan; biosynthesis;

D O I：

10.1271/bbb.60.736

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cell-flee extracts of petioles of Arctium lappa catalyzed enantioselective formation of (+)-secoisolariciresinol [about 20% enantiomer excess (e.e.)] from achiral coniferyl alcohol in the presence of NADPH and H2O2. This is the first report of an enzymatic reaction to afford (+)-secoisolariciresinol enantioselectively.

引用

页码：736 / 737

页数：2

共 17 条

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[Anonymous], 1990, LIGNANS CHEM BBIOLOG

[2]

Bjorkman A., 1957, Svensk Papperstidning, V60, P158

[3]

CHU A, 1993, J BIOL CHEM, V268, P27026

[4] ON THE STEREOSELECTIVE SYNTHESIS OF (+)-PINORESINOL IN FORSYTHIA-SUSPENSA FROM ITS ACHIRAL PRECURSOR, CONIFERYL ALCOHOL [J].