Systemic risk factors for peri-implant bone loss: a systematic review and meta-analysis

被引：101

作者：

Clementini, M. ^{[1
]}

Rossetti, P. H. O. ^{[2
]}

Penarrocha, D. ^{[3
]}

Micarelli, C.

Bonachela, W. C. ^{[4
]}

Canullo, L.

机构：

[1] Univ Roma Tor Vergata, Dept Dent, Rome, Italy

[2] Sagrado Coracao Univ, Oral Biol Program, Sao Paulo, Brazil

[3] Univ Valencia, Dept Oral Surg, Valencia, Spain

[4] Univ Sao Paulo, Dept Prosthodont, Bauru Dent Sch, Sao Paulo, Brazil

来源：

INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | 2014年 / 43卷 / 03期

关键词：

bone loss; risk factors; meta-analysis; systemic diseases; smoking; dental implants; DENTAL IMPLANTS; PLACEMENT PROCEDURES; IL-1; GENOTYPE; SMOKING; OSSEOINTEGRATION; PROGNOSIS; PERIODONTITIS; OVERDENTURES; ASSOCIATION; GUIDELINES;

D O I：

10.1016/j.ijom.2013.11.012

中图分类号：

R78 [口腔科学];

学科分类号：

100302 [口腔临床医学];

摘要：

The aim of this study was to determine the influence of patient-related systemic risk factors (systemic disease, genetic traits, chronic drug or alcohol consumption, and smoking status) on pen-implant bone loss at least 1 year after implant installation and prosthetic loading. An electronic search was performed of MEDLINE, EMBASE, and The Cochrane Central Register of Controlled Trials up to January 2012. One thousand seven hundred and sixty-three studies were identified. After applying a three-stage screening process, 17 articles were included in the qualitative analysis, but only 13 in the quantitative analysis, since smoking was a common exposure. The meta-analysis of these 13 studies (478 smokers and 1207 non-smokers) revealed a high level of heterogeneity and that smoking increases the annual rate of bone loss by 0.164 mm/year. Exposure to smoking had a harmful effect on peri-implant bone loss. However, the level of evidence for oral implant therapy in patients with systemic conditions is very low. Future studies should be improved in order to provide more robust data for clinical application.

引用

页码：323 / 334

页数：12

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