Structure and expression of the mouse S10 gene

被引:13
作者
Zheng, JY [1 ]
Koda, T [1 ]
Arimura, Y [1 ]
Kishi, M [1 ]
Kakinuma, M [1 ]
机构
[1] HOKKAIDO UNIV,INST IMMUNOL SCI,SECT BACTERIAL INFECT,KITA KU,SAPPORO,HOKKAIDO 060,JAPAN
来源
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1997年 / 1351卷 / 1-2期
关键词
GTP-binding protein; Rab; gene structure; gene expression; GTP-BINDING PROTEIN; TRANSPORT; GTPASES;
D O I
10.1016/S0167-4781(97)00022-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We previously reported the cloning of a human S10 cDNA which encodes a small GTP-binding protein belonging to the Rab subfamily. Here we describe a mouse S10 cDNA and its genomic structure. Mouse S10 is 92.3% homologous at the nucleotide level and 98.3% identical at the amino acid level compared to human SIG. The mouse S10 gene is comprised of two exons and a single intron. Northern blotting of tissue RNAs indicates that the S10 gene is predominantly expressed in brain. (C) 1997 Elsevier Science B.V.
引用
收藏
页码:47 / 50
页数:4
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