Regulation of bone formation and vision by LRP5

被引：68

作者：

Patel, MS ^{[1
]}

Karsenty, G ^{[1
]}

机构：

[1] Baylor Coll Med, Houston, TX 77030 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2002年 / 346卷 / 20期

关键词：

D O I：

10.1056/NEJM200205163462011

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1572 / 1574

页数：3

共 18 条

[1] Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow [J].

Bafico, A ;

Liu, GZ ;

Yaniv, A ;

Gazit, A ;

Aaronson, SA .

NATURE CELL BIOLOGY, 2001, 3 (07) :683-686

[2] High bone density due to a mutation in LDL-receptor-related protein 5 [J].

Boyden, LM ;

Mao, JH ;

Belsky, J ;

Mitzner, L ;

Farhi, A ;

Mitnick, MA ;

Wu, DQ ;

Insogna, K ;

Lifton, RP .

NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (20) :1513-1521

[3] LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development [J].

Gong, YQ ;

Slee, RB ;

Fukai, N ;

Rawadi, G ;

Roman-Roman, S ;

Reginato, AM ;

Wang, HW ;

Cundy, T ;

Glorieux, FH ;

Lev, D ;

Zacharin, M ;

Oexle, K ;

Marcelino, J ;

Suwairi, W ;

Heeger, S ;

Sabatakos, G ;

Apte, S ;

Adkins, WN ;

Allgrove, J ;

Arslan-Kirchner, M ;

Batch, JA ;

Beighton, P ;

Black, GCM ;

Boles, RG ;

Boon, LM ;

Borrone, C ;

Brunner, HG ;

Carle, GF ;

Dallapiccola, B ;

De Paepe, A ;

Floege, B ;

Halfhide, ML ;

Hall, B ;

Hennekam, RC ;

Hirose, T ;

Jans, A ;

Jüppner, H ;

Kim, CA ;

Keppler-Noreuil, K ;

Kohlschuetter, A ;

LaCombe, D ;

Lambert, M ;

Lemyre, E ;

Letteboer, T ;

Peltonen, L ;

Ramesar, RS ;

Romanengo, M ;

Somer, H ;

Steichen-Gersdorf, E ;

Steinmann, B .

CELL, 2001, 107 (04) :513-523

[4] The genetic transformation of bone biology [J].

Karsenty, G .

GENES & DEVELOPMENT, 1999, 13 (23) :3037-3051

[5] Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor [J].

Kato, M ;

Patel, MS ;

Levasseur, R ;

Lobov, I ;

Chang, BHJ ;

Glass, DA ;

Hartmann, C ;

Li, L ;

Hwang, TH ;

Brayton, CF ;

Lang, RA ;

Karsenty, G ;

Chan, L .

JOURNAL OF CELL BIOLOGY, 2002, 157 (02) :303-314

[6]

Klibanski A, 2001, JAMA-J AM MED ASSOC, V285, P785

[7] Linkage of a QTL contributing to normal variation in bone mineral density to chromosome 11q12-13 [J].

Koller, DL ;

Rodriguez, LA ;

Christian, JC ;

Slemenda, CW ;

Econs, MJ ;

Hui, SL ;

Morin, P ;

Conneally, PM ;

Joslyn, G ;

Curran, ME ;

Peacock, M ;

Johnston, CC ;

Foroud, T .

JOURNAL OF BONE AND MINERAL RESEARCH, 1998, 13 (12) :1903-1908

[8] MACROPHAGES ARE REQUIRED FOR CELL-DEATH AND TISSUE REMODELING IN THE DEVELOPING MOUSE EYE [J].

LANG, RA ;

BISHOP, JM .

CELL, 1993, 74 (03) :453-462

[9] A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait [J].

Little, RD ;

Carulli, JP ;

Del Mastro, RG ;

Dupuis, J ;

Osborne, M ;

Folz, C ;

Manning, SP ;

Swain, PM ;

Zhao, SC ;

Eustace, B ;

Lappe, MM ;

Spitzer, L ;

Zweier, S ;

Braunschweiger, K ;

Benchekroun, Y ;

Hu, XT ;

Adair, R ;

Chee, L ;

FitzGerald, MG ;

Tulig, C ;

Caruso, A ;

Tzellas, N ;

Bawa, A ;

Franklin, B ;

McGuire, S ;

Nogues, X ;

Gong, G ;

Allen, KM ;

Anisowicz, A ;

Morales, AJ ;

Lomedico, PT ;

Recker, SM ;

Van Eerdewegh, P ;

Recker, RR ;

Johnson, ML .

AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 70 (01) :11-19

[10] Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway [J].

Mao, JH ;

Wang, JY ;

Liu, B ;

Pan, WJ ;

Farr, GH ;

Flynn, C ;

Yuan, HD ;

Takada, S ;

Kimelman, D ;

Li, L ;

Wu, DQ .

MOLECULAR CELL, 2001, 7 (04) :801-809

← 1 2 →