Interspecies transmission of influenza viruses: H5N1 virus and a Hong Kong SAR perspective

被引：82

作者：

Shortridge, KF

Gao, P

Guan, Y

Ito, T

Kawaoka, Y

Markwell, D

Takada, A

Webster, RG

机构：

[1] Univ Hong Kong, Queen Mary Hosp, Dept Microbiol, Hong Kong, Hong Kong, Peoples R China

[2] Univ Wisconsin, Sch Vet Med, Madison, WI 53706 USA

[3] St Jude Childrens Res Hosp, Dept Virol & Mol Biol, Memphis, TN 38105 USA

[4] Tottori Univ, Fac Agr, Tottori 6800945, Japan

[5] Hokkaido Univ, Grad Sch Vet Med, Sapporo, Hokkaido 0600818, Japan

来源：

VETERINARY MICROBIOLOGY | 2000年 / 74卷 / 1-2期

关键词：

influenza; birds; interspecies transmission; Hong Kong; poultry markets; surveillance;

D O I：

10.1016/S0378-1135(00)00174-7

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This account takes stock of events and involvements, particularly on the avian side of the influenza H5N1 'bird flu' incident in Hong Kong SAR in 1997, It highlights the role of the chicken in the many live poultry markets as the source of the virus for humans. The slaughter of chicken and other poultry across the SAR seemingly averted an influenza pandemic. This perspective from Hong Kong SAR marks the: coming-of-age of acceptance of the role of avian hosts as a source of pandemic human influenza viruses and offers the prospect of providing a good baseline for influenza pandemic preparedness in the future. Improved surveillance is the key. This is illustrated through the H9N2 virus which appears to have provided the 'replicating' genes for the H5N1 virus and which has since been isolated in the SAR from poultry, pigs and humans highlighting its propensity for interspecies transmission. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：141 / 147

页数：7

共 21 条

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