Diagnosis and successful in utero treatment of a fetal goitrous hyperthyroidism caused by maternal Graves' disease - A case report

被引:15
作者
Heckel, S [1 ]
Favre, R [1 ]
Schlienger, JL [1 ]
Soskin, P [1 ]
机构
[1] CMCO SCHILTIGHEIM,DEPT OBSTET ULTRASOUND & FETAL MED,F-67042 STRASBOURG,FRANCE
关键词
hyperthyroidism; Graves' disease; fetal thyrotoxicosis; fetal goiter; prenatal diagnosis; fetal blood sampling; fetal therapy;
D O I
10.1159/000264428
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
A case of maternal treated Graves' disease associated with hyperthyroid fetal goiter is presented. Fetal goiter is diagnosed by ultrasound and hyperthyroidism is confirmed by fetal blood sampling. Fetal thyroid status is normalized by maternal carbamizole treatment whereas the mother is euthyroid with replacement therapy after subtotal thyroidectomy. Repeated funipuncture allows us to adjust the fetal treatment. The infant is euthyroid at birth. Pathogenesis, diagnosis and treatment of fetal thyrotoxicosis complicated with maternal Graves' disease are discussed.
引用
收藏
页码:54 / 58
页数:5
相关论文
共 30 条
[1]   DETECTION AND EVALUATION OF FETAL GOITER BY ULTRASOUND [J].
AVNI, EF ;
RODESCH, F ;
VANDEMERCKT, C ;
VERMEYLEN, D .
BRITISH JOURNAL OF RADIOLOGY, 1992, 65 (772) :302-305
[2]   MATURATION OF THYROID-FUNCTION IN NORMAL HUMAN FETUSES [J].
BALLABIO, M ;
NICOLINI, U ;
JOWETT, T ;
DEELVIRA, MCR ;
EKINS, RP ;
RODECK, CH .
CLINICAL ENDOCRINOLOGY, 1989, 31 (05) :565-571
[3]   SONOGRAPHIC FINDINGS IN MATERNAL HYPERTHYROIDISM - FETAL HYPERTHYROIDISM FETAL GOITER [J].
BELFAR, HL ;
FOLEY, TP ;
HILL, LM ;
KISLAK, S .
JOURNAL OF ULTRASOUND IN MEDICINE, 1991, 10 (05) :281-284
[4]  
BROMLEY B, 1992, J ULTRAS MED, V11, P25
[5]  
BRUINSE H W, 1988, Fetal Therapy, V3, P152
[6]   CURRENT CONCEPTS - THE MANAGEMENT OF THYROTOXICOSIS IN PREGNANCY [J].
BURROW, GN .
NEW ENGLAND JOURNAL OF MEDICINE, 1985, 313 (09) :562-565
[7]  
BURROW GN, 1994, NEW ENGL J MED, V331, P1072
[8]  
CHECK JH, 1982, OBSTET GYNECOL, V60, P122
[9]   SUCCESSFUL INUTERO TREATMENT OF FETAL GOITER AND HYPOTHYROIDISM [J].
DAVIDSON, KM ;
RICHARDS, DS ;
SCHATZ, DA ;
FISHER, DA .
NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (08) :543-546
[10]  
FERELMAN AH, 1992, THYROID, V2, P225