A review of repetitive transcranial magnetic stimulation for adolescents with treatment-resistant depression

被引：37

作者：

Magavi, Leela R. ^{[1
]}

Reti, Irving M. ^{[1
]}

Vasa, Roma A. ^{[1
]}

机构：

[1] Johns Hopkins Univ Hosp, Baltimore, MD 21287 USA

来源：

INTERNATIONAL REVIEW OF PSYCHIATRY | 2017年 / 29卷 / 02期

关键词：

Depression; paediatric; repetitive transcranial magnetic stimulation; TERM-FOLLOW-UP; MAJOR DEPRESSION; ELECTROCONVULSIVE-THERAPY; INDUCED SEIZURES; DOUBLE-BLIND; CHILDREN; SAFETY; RTMS; METAANALYSIS; REMISSION;

D O I：

10.1080/09540261.2017.1300574

中图分类号：

R749 [精神病学];

学科分类号：

100204 [神经病学];

摘要：

This review examines the efficacy and safety of repetitive transcranial magnetic stimulation (rTMS) as a treatment for treatment-resistant depression in adolescents. A systematic review of six databases was conducted. Ten multi-subject trials, all uncontrolled, and five case reports met inclusion criteria. Twelve studies focused on treatment efficacy, whereas three studies focused exclusively on adverse events. All efficacy studies focused on adolescents only; 10 of these studies indicated that rTMS may demonstrate some benefit. Improvement within 2-8 weeks was reported in most studies, with a few studies indicating potential long-term benefits. A variety of adverse events occurred including scalp pain, which was the most common, as well as seizures. Controlled studies of rTMS are warranted to further examine whether this treatment is a potential option for adolescents with treatment-resistant depression.

引用

页码：79 / 88

页数：10

共 47 条

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