The role of cell migration and microchimerism in the induction of tolerance after solid organ transplantation

被引:10
作者
Jindal, RM [1 ]
Sahota, A [1 ]
机构
[1] INDIANA UNIV,DEPT MED & MOL GENET,INDIANAPOLIS,IN 46202
关键词
microchimerism;
D O I
10.1136/pgmj.73.857.146
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A new hypothesis has been proposed which states that microchimerism is the basis for the clinical tolerance seen in long-term survivors of solid organ transplants. Efforts to enhance microchimerism include simultaneous infusion of bone marrow of donor origin and transplantation of a solid organ. Studies are in progress to verify the phenomenon of microchimerism and its role in clinical tolerance.
引用
收藏
页码:146 / 150
页数:5
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