Bone cell proliferation on carbon nanotubes

被引：491

作者：

Zanello, LP ^{[1
]}

Zhao, B

Hu, H

Haddon, RC

机构：

[1] Univ Calif Riverside, Dept Biochem, Riverside, CA 92521 USA

[2] Univ Calif Riverside, Ctr Nanoscale Sci & Engn, Dept Chem, Riverside, CA 92521 USA

[3] Univ Calif Riverside, Dept Environm Chem & Engn, Riverside, CA 92521 USA

来源：

NANO LETTERS | 2006年 / 6卷 / 03期

关键词：

D O I：

10.1021/nl051861e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We explored the use of carbon nanotubes (CNTs) as suitable scaffold materials for osteoblast proliferation and bone formation. With the aim of controlling cell growth, osteosarcoma ROS 17/2.8 cells were cultured on chemically modified single-walled (SW) and multiwalled (MW) CNTs. CNTs carrying neutral electric charge sustained the highest cell growth and production of plate-shaped crystals. There was a dramatic change in cell morphology in osteoblasts cultured on MWNTs, which correlated with changes in plasma membrane functions.

引用

页码：562 / 567

页数：6

共 41 条

[1] Nanotubes from carbon [J].

Ajayan, PM .

CHEMICAL REVIEWS, 1999, 99 (07) :1787-1799

[2]

CAFFREY JM, 1989, J BIOL CHEM, V264, P20265

[3] Chemical attachment of organic functional groups to single-walled carbon nanotube material [J].

Chen, Y ;

Haddon, RC ;

Fang, S ;

Rao, AM ;

Lee, WH ;

Dickey, EC ;

Grulke, EA ;

Pendergrass, JC ;

Chavan, A ;

Haley, BE ;

Smalley, RE .

JOURNAL OF MATERIALS RESEARCH, 1998, 13 (09) :2423-2431

[4] Near-infrared fluorescence microscopy of single-walled carbon nanotubes in phagocytic cells [J].

Cherukuri, P ;

Bachilo, SM ;

Litovsky, SH ;

Weisman, RB .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (48) :15638-15639

[5] VOLTAGE-GATED SODIUM AND CALCIUM CURRENTS IN RAT OSTEOBLASTS [J].

CHESNOYMARCHAIS, D ;

FRITSCH, J .

JOURNAL OF PHYSIOLOGY-LONDON, 1988, 398 :291-311

[6] Effect of single wall carbon nanotubes on human HEK293 cells [J].

Cui, DX ;

Tian, FR ;

Ozkan, CS ;

Wang, M ;

Gao, HJ .

TOXICOLOGY LETTERS, 2005, 155 (01) :73-85

[7] VOLTAGE-ACTIVATED AND STRETCH-ACTIVATED BA-2+ CONDUCTING CHANNELS IN AN OSTEOBLAST-LIKE CELL-LINE (UMR-106) [J].

DUNCAN, R ;

MISLER, S .

FEBS LETTERS, 1989, 251 (1-2) :17-21

[8] CHARACTERIZATION OF A VOLUME-SENSITIVE CHLORIDE CURRENT IN RAT OSTEOBLAST-LIKE (ROS-17/2.8) CELLS [J].

GOSLING, M ;

SMITH, JW ;

POYNER, DR .

JOURNAL OF PHYSIOLOGY-LONDON, 1995, 485 (03) :671-682

[9] IMPROVED PATCH-CLAMP TECHNIQUES FOR HIGH-RESOLUTION CURRENT RECORDING FROM CELLS AND CELL-FREE MEMBRANE PATCHES [J].

HAMILL, OP ;

MARTY, A ;

NEHER, E ;

SAKMANN, B ;

SIGWORTH, FJ .

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1981, 391 (02) :85-100

[10]

HEATH JK, 1989, ENDOCRINOLOGY, V124, P3060

← 1 2 3 4 5 →