Correlation between reduced daptomycin susceptibility and vancomycin resistance in vancomycin-intermediate Staphylococcus aureus

被引:324
作者
Cui, LZ
Tominaga, E
Neoh, HM
Hiramatsu, K
机构
[1] Juntendo Univ, Fac Med, Dept Bacteriol, Bunkyo Ku, Tokyo 1138421, Japan
[2] Juntendo Univ, Fac Med, Dept Infect Control Sci, Bunkyo Ku, Tokyo 1138421, Japan
关键词
D O I
10.1128/AAC.50.3.1079-1082.2006
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We present here findings of a strong positive correlation between reduced daptomycin susceptibility and vancomycin resistance in vancomycin-intermediate Staphylococcus aureus (VISA). This correlation is related to cell wall thickening, suggesting that, similar to the case with vancomycin resistance in VISA, the physical barrier of a thickened cell wall may contribute to daptomycin resistance in S. aureus.
引用
收藏
页码:1079 / 1082
页数:4
相关论文
共 20 条
[1]   In vitro activities of daptomycin, arbekacin, vancomycin, and gentamicin alone and/or in combination against glycopeptide intermediate-resistant Staphylococcus aureus in an infection model [J].
Akins, RL ;
Rybak, MJ .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (07) :1925-1929
[2]   Bactericidal activities of two daptomycin regimens against clinical strains of glycopeptide intermediate-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and methicillin-resistant Staphylococcus aureus isolates in an in vitro pharmacodynamic model with simulated endocardial vegetations [J].
Akins, RL ;
Rybak, MJ .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (02) :454-459
[3]   Daptomycin, a new drug class for the treatment of gram-positive infections [J].
Alder, JD .
DRUGS OF TODAY, 2005, 41 (02) :81-90
[4]   Vancomycin-resistant enterococci [J].
Cetinkaya, Y ;
Falk, P ;
Mayhall, CG .
CLINICAL MICROBIOLOGY REVIEWS, 2000, 13 (04) :686-+
[5]   Daptomycin dose-effect relationship against resistant gram-positive organisms [J].
Cha, R ;
Grucz, RG ;
Rybak, MJ .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (05) :1598-1603
[6]   Cell wall thickening is a common feature of vancomycin resistance in Staphylococcus aureus [J].
Cui, L ;
Ma, XX ;
Sato, K ;
Okuma, K ;
Tenover, FC ;
Mamizuka, EM ;
Gemmell, CG ;
Kim, MN ;
Ploy, MC ;
El Solh, N ;
Ferraz, V ;
Hiramatsu, K .
JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (01) :5-14
[7]  
Cui Longzhu, 2003, P187
[8]   Novel mechanism of antibiotic resistance originating in vancomycin-intermediate Staphylococcus aureus [J].
Cui, LZ ;
Iwamoto, A ;
Lian, JQ ;
Neoh, HM ;
Maruyama, T ;
Horikawa, Y ;
Hiramatsu, K .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2006, 50 (02) :428-438
[9]   DNA microarray-based identification of genes associated with glycopeptide resistance in Staphylococcus aureus [J].
Cui, LZ ;
Lian, JQ ;
Neoh, HM ;
Reyes, E ;
Hiramatsu, K .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (08) :3404-3413
[10]   Contribution of a thickened cell wall and its glutamine nonamidated component to the vancomycin resistance expressed by Staphylococcus aureus Mu50 [J].
Cui, LZ ;
Murakami, H ;
Kuwahara-Arai, K ;
Hanaki, H ;
Hiramatsu, K .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (09) :2276-2285