Suppression of male courtship by a Drosophila pheromone receptor

被引：148

作者：

Miyamoto, Tetsuya ^{[1
]}

Amrein, Hubert ^{[1
]}

机构：

[1] Duke Univ, Med Ctr, Dept Mol Genet & Microbiol, Durham, NC 27710 USA

来源：

NATURE NEUROSCIENCE | 2008年 / 11卷 / 08期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1038/nn.2161

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In male Drosophila, chemosensory cues control many aspects of social behavior. We found that males with a mutated Gustatory receptor 32a gene (Gr32a) show high courtship toward males and mated females, indicating that GR32a functions as a pheromone receptor for a male inhibitory pheromone. Notably, we discovered that tarsal Gr32a-expressing neurons were essential for courtship suppression and projected to the ventrolateral protocerebrum, implying direct communication of chemosensory neurons with a higher-order brain structure.

引用

页码：874 / 876

页数：3

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