Anaesthesia for cancer patients

被引:24
作者
Arain, Mujeebullah Rauf [1 ]
Buggy, Donal J. [1 ]
机构
[1] Mater Misericordiae Univ Hosp, Div Anaesthesia Intens Care & Pain Med, Dublin 7, Ireland
关键词
cancer; cancer treatment; chemotherapy; general anaesthesia; radiotherapy; regional anaesthesia;
D O I
10.1097/ACO.0b013e32814f1c34
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Purpose of review Cancer is beginning to outpace cardiovascular disease as the primary cause of death in the developed world. A majority of cancer patients will require anaesthesia either for primary debulking tumour removal or to treat an adverse consequence of the malignant process or its treatment. Therefore we outline here the pathophysiology of cancer, generalized metastatic disease and systemic chemotherapy and radiotherapy on major organ systems. The anaesthetic considerations for optimum perioperative management of cancer patients are discussed, and the possibility of anaesthetic technique at primary cancer surgery affecting long-term cancer outcome is mentioned. Recent findings Cancer and its therapy can adversely affect every major organ system with profound implications for perioperative management. Retrospective analysis suggests an association between regional anaesthetic techniques at primary cancer surgery and reduced incidence of metastatic disease. Summary Optimum perioperative patient care requires individual assessment of the impact of cancer and its treatment on the functional reserve of all major organ systems. The potential of anaesthetic technique at cancer surgery to influence long- term cancer outcome merits investigation.
引用
收藏
页码:247 / 253
页数:7
相关论文
共 48 条
[1]   Attenuation of the tumor-promoting effect of surgery by spinal blockade in rats [J].
Bar-Yosef, S ;
Melamed, R ;
Page, GG ;
Shakhar, G ;
Shakhar, K ;
Ben-Eliyahu, S .
ANESTHESIOLOGY, 2001, 94 (06) :1066-1073
[2]   Drug interactions in oncology [J].
Beijnen, JH ;
Schellens, JHM .
LANCET ONCOLOGY, 2004, 5 (08) :489-496
[3]  
Biki B, ANESTHESIOL IN PRESS
[4]  
BODEY GP, 2000, CLIN ONCOLOGY, P690
[5]  
BORGEAT A, 1993, ONCOLOGY, V50, P456
[6]  
Botz GH, 2005, ACUTE CARE CANC PATI, P117
[7]   Thermoregulation, mild perioperative hypothermia and postanaesthetic shivering [J].
Buggy, DJ ;
Crossley, AWA .
BRITISH JOURNAL OF ANAESTHESIA, 2000, 84 (05) :615-628
[8]  
Celak AJ, 2000, CLIN ONCOLOGY, P797
[9]  
Cormier JN, 2005, ACUTE CARE CANC PATI, P17
[10]   Stress, neuropsychiatric disorders and immunological effects exerted by benzodiazepines [J].
Covelli, V ;
Maffione, AB ;
Nacci, C ;
Tatò, E ;
Jirillo, E .
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, 1998, 20 (02) :199-209