Nanotubes, exosomes, and nucleic acid-binding peptides provide novel mechanisms of intercellular communication in eukaryotic cells: implications in health and disease

被引:136
作者
Belting, Mattias [1 ]
Wittrup, Anders [1 ]
机构
[1] Lund Univ, Dept Clin Sci, Sect Oncol, SE-22185 Lund, Sweden
基金
瑞典研究理事会;
关键词
D O I
10.1083/jcb.200810038
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The prevailing view that eukaryotic cells are restrained from intercellular exchange of genetic information has been challenged by recent reports on nanotubes, exosomes, apoptotic bodies, and nucleic acid-binding peptides that provide novel pathways for cell-cell communication, with implications in health and disease.
引用
收藏
页码:1187 / 1191
页数:5
相关论文
共 31 条
  • [1] Intercellular transfer of the oncogenic receptor EGFrvIII by microvesicles derived from tumour cells
    Al-Nedawi, Khalid
    Meehan, Brian
    Micallef, Johann
    Lhotak, Vladimir
    May, Linda
    Guha, Abhijit
    Rak, Janusz
    [J]. NATURE CELL BIOLOGY, 2008, 10 (05) : 619 - U24
  • [2] Horizontal transfer of oncogenes by uptake of apoptotic bodies
    Bergsmedh, A
    Szeles, A
    Henriksson, M
    Bratt, A
    Folkman, MJ
    Spetz, AL
    Holmgren, L
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (11) : 6407 - 6411
  • [3] Paramutation: From maize to mice
    Chandler, Vicki L.
    [J]. CELL, 2007, 128 (04) : 641 - 645
  • [4] DNA uptake during bacterial transformation
    Chen, I
    Dubnau, D
    [J]. NATURE REVIEWS MICROBIOLOGY, 2004, 2 (03) : 241 - 249
  • [5] Cutting edge:: Membrane nanotubes in vivo:: A feature of MHC class II+ cells in the mouse corneal
    Chinnery, Holly R.
    Pearlman, Eric
    McMenamin, Paul G.
    [J]. JOURNAL OF IMMUNOLOGY, 2008, 180 (09) : 5779 - 5783
  • [6] Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
    Clemens, JC
    Worby, CA
    Simonson-Leff, N
    Muda, M
    Maehama, T
    Hemmings, BA
    Dixon, JE
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (12) : 6499 - 6503
  • [7] Circulating mutant DNA to assess tumor dynamics
    Diehl, Frank
    Schmidt, Kerstin
    Choti, Michael A.
    Romans, Katharine
    Goodman, Steven
    Li, Meng
    Thornton, Katherine
    Agrawal, Nishant
    Sokoll, Lori
    Szabo, Steve A.
    Kinzler, Kenneth W.
    Vogelstein, Bert
    Diaz, Luis A., Jr.
    [J]. NATURE MEDICINE, 2008, 14 (09) : 985 - 990
  • [8] Transport of dsRNA into cells by the transmembrane protein SID-1
    Feinberg, EH
    Hunter, CP
    [J]. SCIENCE, 2003, 301 (5639) : 1545 - 1547
  • [9] Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    Fire, A
    Xu, SQ
    Montgomery, MK
    Kostas, SA
    Driver, SE
    Mello, CC
    [J]. NATURE, 1998, 391 (6669) : 806 - 811
  • [10] Horizontal transfer of DNA and the "genometastasis hypothesis"
    García-Olmo, D
    García-Olmo, D
    Ontañón, J
    Martinez, E
    [J]. BLOOD, 2000, 95 (02) : 724 - 725