Carbazole alkaloids from Murraya koenigii

被引：66

作者：

Chakrabarty, M

Nath, AC

Khasnobis, S

Chakrabarty, M

Konda, Y

Harigaya, Y

Komiyama, K

机构：

[1] BETHUNE COLL,CALCUTTA 700006,W BENGAL,INDIA

[2] KITASATO UNIV,SCH PHARMACEUT SCI,TOKYO 108,JAPAN

[3] KITASATO INST,TOKYO 108,JAPAN

来源：

PHYTOCHEMISTRY | 1997年 / 46卷 / 04期

关键词：

Murraya koenigii; Rutaceae; curry leaf plant; roots; 9-carbethoxy-; and; 9-formyl-3-methylcarbazoles; cytotoxicity;

D O I：

10.1016/S0031-9422(97)00345-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new alkaloids, 9-carbethoxy-3-methylcarbazole and 9-formyl-3-methylcarbazole, and a known metabolite, 3-methyl-carbazole were isolated from the roots of Murraya koenigii. All three compounds were identified by detailed spectral analyses including 2D NMR studies and their structures confirmed by synthesis. Of the two new metabolites, the 9-formyl compound displayed weak cytotoxicity against both mouse melanoma B16 and adriamycin-resistant P388 mouse leukemia cell lines. (C) 1997 Elsevier Science Ltd.

引用

页码：751 / 755

页数：5

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